Usual Suspects name and Ag Flashcards

1
Q

MNS major Antigens
chromosome location

A

M,N,S,s,U
chrom 4

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2
Q

ABO
major Ags
chromosome

A

A,B,O,AB
chromosome 9

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3
Q

Rh
major Ags
chromosome

A

D,C,c,E,e
chromosome 1

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4
Q

P
major ags
chromosome

A

also known as P1PK

Ags: P1,P2,p
chrom 22

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5
Q

Kell ags
chromosome

A

KEL

K,k,Kpa
Kpb, Jsa, Jsb

Chrom 7

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6
Q

Lewis ag
chromosome

A

LE

Lea and Leb

chrom 19

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7
Q

Duffy Ag
chrom

A

FY
Fya, Fb, Fy3

chrom 1

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8
Q

Kidd Ag
chrom

A

Jk

Jka, Jkb, JK3

chrom 18

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9
Q

Lutheran
Ag
chrom

A

LU

Lua
lub

chrom 19

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10
Q

ABO
temp
immunoglobulin
compliment
special features

A

cold rxn
IgM
fixes compliment
reverse type
naturally occuring
HTR

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11
Q

Rh
antitheticals
temperature
ig
compliment
special features

A

D,C,c,E,e
warm reactive
IgG
DONT fix compliment
ENHANCED by enzymes
associated w HDN

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12
Q

Kidd ag
temp
ig
compliment
special features

A

Jka Jkb (Jk3 null<-most common)
warm reactive
IgG
Fix compliment
ENHANCED BY ENZYMES
Hide and Seek/DOSAGE
2m urea

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13
Q

Kell ag
temp
ig
compliment
special features

A

K-k
kpa Kpb
jsa Jsb

K/b high frequency

warm reactive IgG
DO NOT FIX compliment

DTT destroys
HDN severe
Acanthocytes with null

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14
Q

Duffy ag
temp
ig
compliment
special features

A

Fya Fyb
warm reactive IgG
ENZYMES DESTORY
malaria vivax
(Fya-b-)
Syntentic Rh-chrom 1

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15
Q

lutheran ag
temp
ig
compliment
special features

A

Lua Lub (lub more common)

IgG- warm reactive lub
IgM - cold reactive Lua

DONT FIX COMPLIMENT

DTT Destroys
mixed field special feature

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16
Q

Lewis ag
temp
ig
compliment
special features

A

Lea (le) Leb (se) not antetheticals
Cold rxn IgM
DONT FIX COMPLIMENT

fall off cell in a week
not clinically significant
can interfere w reverse type

17
Q

P ag
temp
ig
compliment
special features

A

P1/Pk/p/P
cold rxn IgM anti-pI

DONT FIX COMPLIMENT
not destoryed/enhanced by enzymes

Donathanlandsteiner ab and PCH

18
Q

MNS ag
temp
ig
compliment
special features

A

M-N
s-S
U (Mk/Ena)

Cold IgM (M/N)
Warm IgG (s/S)

all destroyed by enzymes
dOSAGE

M/N clinically significant