Organic Pathways - Aromatic Flashcards
1
Q
Benzene to ketone
A
Acyl chloride in the presence of anhydrous AlCl3 catalyst
Electrosub
2
Q
Ketone to alcohol
A
NaBH4
Nuc.add
3
Q
Benzene to nitrobenzene (NO2)
A
Conc HNO3
Conc H2SO4
ElectroSub
4
Q
nitrobenzene (NO2) to aminobenzene (NH2)
A
Sn and HCl
Reduction
5
Q
Why would you choose the route that only produces one product
A
- multiple products can be difficult to separate and result in lower yields
6
Q
Why would you choose the route that has a higher atom economy
A
Less waste
7
Q
Why would you choose the route that has fewer steps
A
Higher yields
8
Q
Why would you choose the route that needs no/less solvents
A
- solvents can be toxic/dangerous
- it can be difficult/expensive to dispose of them
