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Miller's Anesthesia > 49. Blood management > Flashcards

49. Blood management Flashcards

1
Q

CMV and blood management

A

FFP and cryo are safe because they are leukoreduced components

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1
Q

CDPA1

A

Citrate Anticoagulation
Dextrose energy for RBC
Phosphate
Adenosine (increase survival from 21 to 35)
storage from 1 to 6 degrees (inhibits Na/K pump)

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2
Q

Platelets requirements for surgery

A

> 20 spinal tap
50 surgery
100 neurosurgery

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3
Q

IS phase definition and use

A

Check against errors in ABO typing. Takes 5 min
For emergency
Safe 99%

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4
Q

Hemorrhagic diathesis after blood

A

After 20 units 30%
After 25 90%
After 30 100%

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5
Q

Delayed hemorrhagic reaction

A

2 - 21 days after
By autoantibodies (not detectable in blood)

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6
Q

Window period for infections

A

HC 3 - 4 d
HIV 5 - 6
Hb 24
HTLV 51

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7
Q

Cryo contents

A

Factor 8, 13, vW, fibrinogen, fibronectin

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8
Q

TRALI charac

A

1 - 3%
after 6 h
Non cardiogenic pulmonary edema
Most common source FFP or whole blood

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9
Q

What fluids to give with PC

A

Dextrose 5% + saline 0.45
Dextrose 5% + 0.9 salline
0.9 saline
Normosol

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10
Q

PF24 vs FFP

A

PF24 less factor 5 8 compared to FFP

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11
Q

PC

A

Hct 57%
pH 6.8
HCO3 11
K 20
Na 126
Gluc 24

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12
Q

DIC tests

A

PT long
Fibrinogen low
BT long

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13
Q

Acute hemorrhage clasification

A
  1. < 750 HR 100 RR 14-20 UO 30 Blood loss 15%
  2. 750 - 1500 100 20-30 20-30 15-30
  3. 1.5 - 2 120 30-40 20-10 30-40
  4. > 2 >140 >40 <10 >40
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14
Q

When is not possible to use cell savage

A

If we use hypotonic fluids on the surgery

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15
Q

Contraindications for autologous blood donation

A
16
Q

Adsol

A

Adenine glucose mannitol NaCl
Extended until 42 days
Htc 50-60%

17
Q

Survival rate pf RBC after 35 days

A

70%

18
Q

Ptl transfusion

A

At room temperature
Can be without ABO
Risk of infection (syphilis)

19
Q

Life spam of platelets in whole blood

A

24 hours

19
Q

ABO compatibility testing

A
20
Q

Where can you see very low and low platelet count?

A

Very low in TTP
Low in DIC and end stage liver failure

21
Q

Rate for significant hyperK with blood transfusion

A

More than 120 ml/min

Miller's Anesthesia (43 decks)

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