Lab5 Neoplasia Images Flashcards
Is this tumor of the breast malignant or benign? How can you tell?
Benign
You can see on far right that it is encapsulated
Is this tumor of the breast benign or malignant?
Malignant
It is invading and destroying adjacent cells [on right you can see
Are these smooth muscle neoplasias benign or malignant? Naming?
Left is benign: leiomyoma
Right is malignant: meiomyosarcoma
Are these squamous epithelial neoplasias benign or malignant? Name?
Left is benign = squamous papilloma
Right is malignant = squamous cell carcinoma
Are these glandular epithelium neoplasias benign or malignant? Naming?
Left is benign = adenoma
Right is malignant = adenocarcinoma
Which image is hamartoma and which choristoma?
Left = hamartoma
Right = choristoma
Which is parenchyma and which stroma in this carcinoma of colon?
Left = parenchyma
Right = stroma
Name these plasias from left to right
- Hyperplasia [of lactating breast]
- Metaplasia [of respiratory epithelium]
- Dysplasia [of colonic epithelium]
- Desmoplasia [of colon adenocarcinoma]
Do I need to memorize this?
No idea
With normal left, abnormal right – what is the change demonstrated? What is this called?
Pleomorphism
Variation in size and shape
Cells and nuclei become less uniform
How are nuclei changed in abnormal? Whis is normal and which abnormal?
abnormal nuclear morphology
higher nucleus: cytoplasm ration
large nuclei, irregular, hyperchromatic
Whis is abnormal and which abnormal? What is change in the cells?
left is abnormal
right is normal
left shows increased proliferative activity
more cells undergoing mitosis
atypical shape
Whis is normal and which is abnormal? What is the change
Left is normal
right is abnormal
Shows loss of architecture, haphazard growth, irregular glands
Which is benign and which is malignant?
Left = benign: very well differentiated
Right = malignant: less well differentiated
Which of these is normal squamous , which dysplasia, and which carcinoma un situ?
- top right is normal
- bottom is dysplasia
- top left is squamous cell carcinoma in situ
Seems important but hard to make note card
Eek
What type of plasia is this? [hint compare left and right sides of this image, left is normall]
dysplasia
loss of cell uniformity/orientation
What cell change does the upper right side of this image of a tumor show? Why?
Coagulative necrosis
Tumor has outgrown its blood supply, get ischemia
What type of stroma surrounding these neoplastic glands? What is this change called and what is its sgnificance
densely fibrotic stroma
called desmoplasia
implies that these glands are invasive
