MGD Flashcards
1
Q
What is pK?
A
The likelihood that an acid will dissociate.
Weak acids have high pKs
2
Q
How are enzymes regulated?
A
By changing the concentration of the product or the substrate
By changing enzymes conformation
Changing rate of protein synthesis/degradation
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3
Q
What factors are upregulated by thrombin the the blood clotting cascade?
A
5, 8 and 11
4
Q
What blood clotting factors undergo post-translation modification by vitamin k?
A
2, 7, 9 and 10
5
Q
What happens to procollagen to make collagen?
A
Hydroxylated and phosphorylated. Then makes disulphide bonds and chains wrap together to make triple helix. Leave cell in vesicles as tropocollagen and then n and c terminal peptides are removed and strands join together by covalent bonds to make large fibre - collagen
