17.6.2013(pediatrics)40

Question 0

Epilepsy in autism

Answer 0

1/5 to 1/3

Question 1

Mental retardation in children with autism

Answer 1

75%

Question 2

Onset of autism

Answer 2

Before age of 3 years

Question 3

Specific marker for autism

Answer 3

Two or more trophoblastic inclusions

Question 4

3 essential criteria for diagnosis of autism

Answer 4

Impaired social interaction
Impaired communication
Restricted, repetitive range of interests,behaviours,activities

Question 5

Seizure disorder with loss of language skills

Answer 5

Landu kleffner syndrome

Question 6

Age of onset of landu kleffner syndrome

Answer 6

5 1/2 years

Question 7

Landu kleffner syndrome is common in

Answer 7

Boys

Question 8

DD for landu kleffner syndrome

Answer 8

Autism

Question 9

DOC for landu kleffner syndrome

Answer 9

Sodium valproate

Question 10

CT and MRI in landu kleffner syndrome

Answer 10

Normal

Question 11

Rx of Lennox gestaut syndrome

Answer 11

Ketogenic diet

Question 12

Rolandic epilepsy

Answer 12

Benign childhood partial epilepsy with centrotemporal spikes

Question 13

Age of onset of rolandic epilepsy

Answer 13

9-10yrs

Question 14

Presentation of rolandic epilepsy

Answer 14

Partial seizures

Motor and sensory symptoms are often confined to face

Question 15

Prognosis of rolandic epilepsy

Answer 15

Excellent

Spontaneous remission after 14-16yrs

Question 16

Rx of rolandic epilepsy

Answer 16

Carbamazepine for 2 years

Question 17

Rasmussen encephalitis

Answer 17

Subacute inflammatory encephalitis

Question 18

Rasmussen encephalitis presents as

Answer 18

Epilepsia partialis continua

Question 19

Cause of Rasmussen encephalitis

Answer 19

Autoantibodies that stimulate glutamate receptors

Question 20

Prognosis of Rasmussen encephalitis

Answer 20

Poor

Question 21

Progressive Myoclonic epilepsy

Answer 21

Lafora disease

Question 22

Mental deterioration is characteristic feature of

Answer 22

Lafora disease

Question 23

Presentation of Lafora disease

Answer 23

Initially GTCS,later Myoclonic jerks

Question 24

Lafora bodies are seen in

Answer 24

Eccrine sweat gland duct cells

Question 25

Gene involved in Lafora disease

Answer 25

6p | Codes for tyrosine phosphatase

Question 26

Cause of renal artery stenosis in young

Answer 26

India(Takayasu) | West(Fibromuscular dysplasia)

Question 27

Bleeding from umbilical stump suggests

Answer 27

Factor XIII deficiency

Question 28

Test to detect factor XIII deficiency

Answer 28

Clot stability in 5M urea

Question 29

Why Von willi brand disease pts don't present in neonatal period

Answer 29

Plasma Von willi brand levels are high(maternal)

Question 30

Presentation of factor XIII deficiency

Answer 30

Bleeding Delayed wound healing Infertility in males Abortion in females

Question 31

Physiological jaundice,duration

Answer 31

``` Phase 1 5 days(term infants) 12mg/dl 7 days(preterm infants) 15mg/dl Phase 2 Values decline to 2mg/dl which lasts for 2 weeks ```

Question 32

Breast feeding jaundice,onset

Answer 32

1 week

Question 33

Cause of breast feeding jaundice

Answer 33

Reduced feed Dehydration Unconjugated hyperbilirubinemia

Question 34

Breast milk jaundice,onset

Answer 34

4-7 days | May continue till 3rd month

Question 35

Cause of breast milk jaundice

Answer 35

Inhibitors of conjugation present in breast milk Beta pregananediol Free fatty acids

Question 36

Primary prophylaxis should be given within

Answer 36

9 days

Question 37

Drugs not used for primary prophylaxis

Answer 37

Tetracyclines | Sulpha drugs

Question 38

Secondary prophylaxis of rheumatic fever

Answer 38

Prevention of colonisation of URI in pts who already had a previous attack of RF or established RHD

Question 39

Drugs used for primary prophylaxis of RF

Answer 39

``` Benzathine pencillin 1.2M units i.m single dose Penicillin V for 10 days Erythromycin Cephalexin Cefadroxil Clindamycin Azithromycin Erythromycin Clarithromycin ```

Question 40

Secondary prophylaxis duration

Answer 40

21 years of age or 5 years after the last attack of RF whichever is later If heart disease is present life long prophylaxis or atleast till 40 yrs of age

Question 41

Secondary prophylaxis,drugs

Answer 41

Benzathine pencillin 1.2MU every 3-4 weeks | Pencillin V 500mg bd

Question 42

Secondary prophylaxis in penicillin allergic pt

Answer 42

1.SULPHADIAZINE Penicillin and sulfonamide allergy Macrolides

Question 43

Type of rickets not associated with myopathy

Answer 43

X linked hypophosphatemic rickets

Question 44

Diff btw hypophosphatemic and calcium deficient rickets

Answer 44

``` No tetany No dental enamel hypoplasia No profound myopathy No rachitic rosary and Harrison sulcus In hypophosphatemic rickets ```