185 FINAL EXAM Flashcards
(147 cards)
Benzodiazepine, anti-anxiety, muslce relaxant, anti-convulsant
- Short acting
Use: Sedative (given in pre-op)
- Amnesia effect, produces sleep
Side effects:
- Drowsiness
- Confusion
- Hypotension
- Hepatotoxicity
- Low HR
Interventions: Vitals
Antidote: Flumazenil (Romazicon)
Midazolam
Dissolves chemical bonds w/in mucus making it separate/ liquiefying/ reducing viscosity
- Given as nebulizer
Use: Pneumonia, emphysema, asthma, & bronchitis
Side effects:
- N/V
- Tachycardia
- Hypotension
- Rotten egg oder
- Bronchospams (adverse)
Interventions:
- Vitals
- monitor cough & bronchial secretions
- Record GI symptoms before/after therapy
Antidote for Tylenol OD - Given PO
Mucomyst (Acetyl Cysteine)
Inhibits interaction of acetylcholine at recepter site on bronchial smooth muscle, resulting in bronchodilation
Use: Asthma, long term Tx or reversible bronchospasms associated w/ COPD
Adverse:
- Mouth dryness
- Throat irritation
- Dizziness
- Nasal congestion
Serious effects:
- Tachycardia
- Urinary retention
- Exacerbation of symptoms
Interventions:
- Vitals
- monitor cough & bronchial secretions
- Record GI symptoms before/after therapy
Ipratropium (Atrovent)
Corticosteroid - PO
- Decreases inflammation
- Caution w/ Diabetes (increases BS)
Use: severe inflammation, MS, asthma, COPD, pulmonary fibrosis
Side effects:
- Weight gain
- Depression, mood changes
- Poor wound healing
- Decreased immunity
Patient teaching:
- DO NOT STOP ABRUPTLY
- Taper off as Dr. directed
Prednisone
Deficiency of Pituitary hormone (TSH - Secondary hypothyroidism)
Deficiency of TSH decreases secretion of thyroid hormones
S/s:
* Decreased metabolic rate
* Lethargy, forgetfulness, irritability
* Headache, constipation
* Decreased HR, dyspnea
* Swelling/edema, dry/thick skin
* Coarse hair
Tx:
* Hormone replacement therapy - most commonly Levothyroxine (Synthroid)
Hypothyroid
Abnormal increased synthesis & secretions on the thyroid gland w/ overproduction of the thyroid hormone T3/T4 resulting inexaggeration of the metabolic processes
- Geaves disease & Multinodular goiter most common
S/s:
* Weight loss, hair loss, insomnia
* Intolerance of heat, personality changes
* Tachycardia, increased systolic BP/ HTN
* Afib, increased metabolic rate
* Edema to neck, termors, exophthalamos (eye buldging)
Tx:
* Radiation: destroys thyroid tissue, decreases homrone production
* Surgery: Thyroidectomy
* Drug therapy: Tapazole, PTU, Beta blockers, Iodides, Antithyroids, ect
Hyperthyroid
(Graves disease or Thyrotoxicosis)
What labs determine the diagnosis of hypothyroid?
Determination of free T4 & TSH
* Free T4 is low w/ hypothyroidism
Large amounts of thyroid hormone enter the bloodstream during surgery or when patients w/ severe hyperthyroidism develop a severe illness of infection
Approx. 12hrs after surgery is when s/s will occur
S/s:
- Tachycardia, cardiac dysrhythmias
- Vomiting, fever, confusion
Thyroid Storm
What electrolyte deficiency may occur with a thyroidectomy?
Hypocalcemia
Hypomagnesemia
low level of calcium in the blood (below 8)
* Results from diarrhea, inadequate dietary intake of vit. D, multiple blood transfusions, ect.
hypoalbuminemia is the most common
S/s:
* Trousseau’s sign
* Chvostek’s sign
* diarrhea
* tingling of fingertips and mouth, severe muscle cramps
* laryngospasms (most severe)
* Cardiac dysrhythmias, seizures
treat with oral or IV supplements
hypocalcemia
Synthetic hormone - IV,IM, PO
Use: Hypothyroidism, Myxedema coma, Thyroid replacement
Side effects:
* Anxiety, tachycardia
* Angina, HTN,palpitations, tachycardia
* N/V/H, cramps
* Thyroid storm (Adverse)
* Cardiac arrest (Adverse)
Nursing considerations:
* Assess BP & pulses periodically
* Daily weight (same time, clothes, ect)
* Monitor cardiac status
* Monitor vitals & labs T3/T4
BBW: Obesity Tx - Not taken to decrease weight
Education:
* Don’t switch brands unless approved
* Take in AM on empty stomach 30 min before food
* Monitor anticoagulent level & adjust dose PRN
Levothyroxine (synthroid, eltroxin, Levo-T)
Use: Makes thyroid hormones, bone & brain development in pregnancy
Route: PO, IV
Side effects:
* Burning mouth, throat, and stomach
* N/V/D/fever
* Weak pulse (adverse)
* Coma (adverse)
* Thyroid gland inflammaiton/cancer (adverse)
Nursing considerations:
* Monitor HR
* Monitor for hypersensitivity and GI bleed
BBW: Hepatic disease, No breastfeeding
Education:
* Take prenatals or Iodine supplements if preg
* Report abnormal bleeding
Iodine
Use: Prep for thyroidectomy, thyrotoxic crisis, hyperthyroidism, & thyroid storm
Route: PO
Side effects:
* N/V/D/H
* Vertigo
* Rash, alopecia
* Jaundice
* Liver failure
* Death
Nursing consideration:
* Assess for weight loss, fever, constipation, & weakness
* Monitor T4 (increases)
BBW: Hepatic disease, No breastfeeding
Education:
* Report redness, swelling, sore throat, mouth lesions, yellow skin/eyes, and dark stool/urine
Propylthiouracil (PTU)
Inhibits the synthesis of the thyroid hormones
Used after course of PTU
Used w/ a Lugol solution & SSKI (5% iodine & 10% SSKI)
Some relief w/in 24hrs
Can cause discoloration to teeth & gastric upset
Iodides
Excessive cortisol
Hypersecretion of the adrenal cortex resulting in production of excess amounts of corticosteroids
Causes:
* Endogenous - Pituitary tumor/ Adrenal tumor
* Exogenous - Prolonged admin. of high dose corticosteroids
S/s:
* Moon face, Buffalo hump
* Trucal obestiy, purple straie on abd., breast, or butt
* Hypokalemia, hyperglycemia, poor wound healing
* HTN
Tx/ interventions:
* Drug therapy: Mitotane, Metyrapone
* Radiation: Internally/Externally, destroys tissue
* Surgery: Transsphenodial hypophysectomy (pituitary gland), Adrenalectomy (adrenal tumor)
* Vitals & labs
* Skin assessment
* Educate on wearing a medical band
* Monitor for SI
* Caution on long term use of some herbs (celery, juniper, licorice, & parsley - Causes hypokalemia)
Cushings syndrome
What labs/tests can you use to Dx Cushings syndrome?
Labs:
* Plasma cortisol levels (High)
* ACTH (high)
Tests:
* Xray
* CT, MRI
* Angiography
What patient education would be provided for a Pt Dx w/ Cushings syndrome?
Do not blow nose (after surgery)
Monitor bleeding
Wound care (packing)
S/s of infection (Smell breath & packing if drainage)
What surgical intervention willl occur if their is a pituitary tumor causing Cushings disease?
Transsphenoidal microsurgery
Removal of adrenal glans
Post-op care:
* Admit to ICU
* Monitor vitals for s/s of shock
* monitor kidneys & strict I/Os
* Give vasopressor to decrease BP & HR
Adrenalectomy
Destructive disease process affecting adrenal glands that cause deficiencies of cortisol & aldosterone
* Most common cause is auto immune (adrenal tissue destroyed by antibodies formed by immune system)
Secondary adrenal insufficiency is the result of the hypothalamus or pituitary which caused decreased androgen & cortisol production
* Include oituitary tumors, radiation therapy, ect
S/s:
* Orthostatic hypotension
* Skin hyperpigmentation
* Hypoglycemia, hyponatermia, hyperkalemia
* Severe headaches, abd. pain, joint pain
* Wight loss, weakness/fatigue
* Salt cravings
Interventions/Tx:
* Restore fluids/ electrolytes
* Low K diet, high Na diet
* Replace adrenal hormone (Hydrocortisol)
* Assess for addisons crisis
* Carry medical kit & 100mg od IM hydrocortisone/dexamethasone
* Take meds as ordered
* Educate on life long therapy & monitoring
Addisons Disease (Adrenal Hypofunction of pituitary)
Life threatening emergency caused by insuffieicient adrenocortical hormones / sudden sharp drop in hormones
S/s:
* hypotension
* Tachycardia
* Dehydration (N/V)
* High temp
* Cyanosis
* Progresses to vasomotor collapse/ possible death
Interventions/Tx:
* IV fluids (Isotonic/ Hypertonic/ D5LR)
* Hydrocortisone
* Electrolyes
* Dextrose to restore normal BP
Addisons crisis
What electrolyte imbalances occur w/ Addisons disease?
Hypercalemia
Hyperkalemia
Hyponatremia
Hypoglycemia
Tip: Hyper before Hypo
What electrolyte imbalances occur w/ Cushings disease?
Hypocalemia
Hypokalemia
Hypernatremia
Hyperglycemia
Tip: Hypo before Hyper
Steroid - PO/IV/IM
Use:
* Severe inflammation, UC
* Adrenal Insufficiency, COPD
Side effects:
* Depression, mood changes
* Flushing, Increased appetite
* HF, HTN
Interventions:
* Vitals & labs (CBC,BMP)
* Monitor for depression
Hydrocortisone