Parathyroid

Question 1

bisphosphonates used to treat hypercalcemia

Answer 1

pamidronate and zoledronic acid

Question 2

MOA bisphosphonates

Answer 2

inhibit bone resorption

Question 3

rapid acting tx for hypercalcemia

Answer 3

calcitonin (inc urinary ca excretion)

Question 4

aim when treating hypercalcemia

Answer 4

dec serum calcium by expanding volume (Saline), inc ca excretion (calcitonin) and inhibit bone resorption (bisphosphonates)

Question 5

reasons for secondary hyperPTH

Answer 5

renal disease (don’t activate Vit D and retain phosphate) or just Vit D deficient… body thinks there is low Ca

Question 6

Vit D supplements for deficiency

Answer 6

cholecalciferol & ergocalciferol

Question 7

acute hypocalcemia tx

Answer 7

calcium gluconate

Question 8

persistent hypocalcemia tx

Answer 8

oral Ca and Vit D

Question 9

active vit D

Answer 9

calcitriol

Question 10

tx of hypocalcemia due to renal failure

Answer 10

calcitriol (vit D) + phosphate binders (calcium carbonate or acetate, sevelamer)