repro Flashcards
antiestrogen on breast, proestrogen on endometrium and bone
tamoxifen
blocks estrogen in hypothal (hyopthal thinks there isn’t enough estrogen)
clomiphene citrate (so inc LH and leads to ovulation)
micronized natural progesterone
prometrim
transvaginal natural progesterone
crinone
synthetic progestins
medroxyprogesterone, norethinidrone, nogestrel megestrol
progesterone only BC
norethindrone, nogestrel
use of progestin BC only
estrogen contraindicated ie endometrial Ca history, lactating
Estrogen/Progesterone BC combo physio
estrogen: suppress FSH thus preventing follicle maturation and LH surge.
Progesterone, suppress LH thus preventing ovulation, and thickens mucus so sprem can’t penetrate and atrophies endometrium.
poscoital BC
levonorgestrel
detachment of uterus
mifepristone (RU-486)
ED meds
sildenafil citrate, vardenafil, tadalafil
MOA ED meds
inhibit cGMP breakdown, dec Ca, smooth muscle relaxation, erection. CI with nitrates and alpha blockers