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Antimicrobials > Cell Wall Inhibitors > Flashcards

Cell Wall Inhibitors Flashcards

1
Q

class of penicillin G?

A

Narrow spectrum

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2
Q

Class for Naficillin?

A

very narrow spec

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3
Q

Class of methicillin?

A

Very Narrow spec

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4
Q

Class of oxacillin?

A

Very narrow spec

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5
Q

Use of very narrow spectrum?

A

Staphylococci (Non MRSA)

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6
Q

Range of narrow spectrum penicillins?

A

streptococci, meningococci, pneumococci, Trepenoma

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7
Q

Two penicillins excreted in bile?

A

naficillin, oxacillin

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8
Q

cefazolin

A

G1 ceph

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9
Q

cephalexin

A

G1 ceph

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10
Q

Use of G1 cephalosporins?

A

Gram positive cocci (not MRSA), e coli, klebsiella, porteus (PEcK

Surgical prophylaxis, no CNS activity

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11
Q

Cefotetan

A

G2 HENS (H flu, enterobacter, Neisseria, S. marcescens)

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12
Q

Cefaclor

A

G2

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13
Q

Cefuroxime

A

G2 crosses CNS

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14
Q

Ceftriaxone

A

G3

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15
Q

Cefotaxime

A

G3

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16
Q

Cefdinir

A

G3

17
Q

Cefixime

A

G3

18
Q

Class used for empiric treatment of meningitis and sepsis?

A

G3 cephalosporins, CNS coverage

19
Q

class of cephs resistance to betalactamases?

A

G4

20
Q

what two cephs are eliminated in bile?

A

cefoperazone (?) ceftriaxone

21
Q

What two cephalosporins have disulfiram like effects?

A

cefoperazone, cefotetan (G3s)

22
Q

organisms not covered by cephalosporins?

A

Listeria, Atypicals (mycoplasma, chlamydia), MRSA, enterococci

23
Q

Empiric use in life-threatening nosocomial infections?

A

imipenem/meropenem

24
Q

What drug is given with imipenem to block nephrotoxic metabolite production?

A

Cilastatin

25
Q

major SE of imiopenem

A

50% have seizures

26
Q

Used for Gram negative rods (pseudomonas) in those with penicllin allergy?

A

aztreonam

27
Q

3 side effects of vancomycin

A

red man syndrome (histamine) ototoxic, nephrotoxic

Antimicrobials (3 decks)

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