Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

HEMA 2 > 1st Lecture - Prelim > Flashcards

1st Lecture - Prelim Flashcards

(54 cards)

Start Studying
1
Q

defined as a method for controlling infection

A

Universal precaution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

defined as all blood and certain body fluids are treated as if infected with hepa B, HIV, or disease-producing blood-borne pathogens

A

Universal precaution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Biohazard waste bin is in color?

A

yellow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

sharps waste bin is in color?

A

red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

helps in diagnosing bleeding disorder

A

platelet count

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

platelet functions?

A
  1. Primmary hemostasis
  2. Maintaning Capillary integrity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Platelet: Normal range?

A

150,000 - 450,000 /mm3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Largest hematopoietic stem cell in bone marrow

A

megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

megakaryocyte maturations involves –?– where nuclear material reduplicates but nucleus does not divide

A

endoreduplication / endomitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

platelets arise from what cell

A

megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

carrier of CD34

A

progenitor cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

carrier of CD42

A

Terminal differentiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

3 progenitor cells

A
  1. BFU-Meg
  2. CFU-Meg
  3. LD-CFU-Meg
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

3 Terminal Differentiation Cells

A
  1. MK-I
  2. MK-II
  3. MK-III
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Size: 20 - 50 um
Cytoplasm: non granular, small blunt pseudopods

A

Megakaryoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Size: 20 - 60 um
Cytoplasm: granules START to form
Nucleus: may show lobulation

A

Promegakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Size: 30 - 90 um
Cytoplasm: finely and diffusely granular
Nucleus: multi-lobulation, chromatin is coarser, no nucleoli visible

A

Granular Megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Size: 40 - 120 um
Cytoplasm: course clumps of granules aggregating into little bundles which bud off (platelets)
Nucleus: multi-lobulation, no nucleoli visible

A

Mature Megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

last stage of megakaryocytic series which has no visible nucleoli

A

Mature Megakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

stage of megakaryocytic series which granules begin to form

A

Promegakaryocyte

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

smallest among the stages of megakaryocytic series

A

Megakaryoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Product of the megakaryocytic series

22
Q

2 - 4 um

23
Q

cytoplasmic fragments of megakaryocyte

24
Platelets survive within how many days
7-10 days
25
1/3 of platelets are found in?
circulating pool
26
2/3 of platelets are found in?
splenic platelet pool
27
Anatomical parts of Platelet
1. Peripheral zone 2. Sol-gel zone 3. Organelle zone 4. Membranous system
28
Platelet Normal function range:
>100,000/uL
29
Platelet hemorrhage range:
<10,000/uL
30
platelet participate in hemostasis by providing negative charge phospholipid surface for ?
Factor V & Factor 2 Activation
31
platelet participate in hemostasis by releasing substances that mediate ?
vasoconstriction, platelet aggregation, coagulation and vascular repair
32
platelet participate in hemostasis by providing surface glycoproteins such as?
GP Ib and IIb/IIIa
33
Peripheral zone is responsible for?
platelet adhesion and aggregation
34
adhesion is?
attachment of platelets to the blood vessel
35
aggregation is ?
attachment of platelets to each other
36
The outer part of the Peripheral zone that is composed of glycoproteins
glycocalyx
37
Glycocalyx is a Major GP responsible for?
Primary hemostasis
38
A receptor for Von Willebrand factor responsible for platelet adhesion
GP Ib
39
A receptor for Fibrinogen responsible for platelet aggregation
GP IIb/IIIa
40
Parts of the Peripheral zone
glycocalyx, plasma membrane, and submembranous system
41
Sol-gel zone is composed of
microfilament and microtubule
42
Under microfilaments, the proteins found are responsible in creating contractile protein such as?
actomyosin or trombasthenin
43
actomyosin or trombasthenin is important for clot ---?
clot retraction
44
it is composed of tubulin
microtubule
45
protein tubulin maintains the ---- of the platelet
shape
46
Organelle zone is composed of?
mitochondria, alpha granules, & delta granules
47
how many alpha granules is found per cell
50 - 80 per cell
48
how many delta granules is found per cell
2 - 7 per cell
49
It contains the ADP, ATP, Serotonin, Ca+ and Mg
Delta granules
50
It contains Von Willebrand factor, factor 5, factor 4, etc
Alpha granules
51
membranous sytem comprises of
Dense Tubular System and Open Canalicular System
52
Dense tubular system is an endoplasmic reticulum that sequesters --?--- for platelet activation
calcium
53
Open Canalicular System is the ---?--- of the plasma membrane for release of granule content during platelet activation
invagination

HEMA 2 (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions