2

Question 1

Clinical findings a/w poor prog in CHF?

Answer 1

resting tach
S3 gallop
incr JVP
decr BP
mod/severe MR
low max O2 consumption (peak VO2)

Question 2

Glactokinase def:

Answer 2

cataracts

Question 3

Galactose 1P UT def:

Answer 3

hypogly, FTT, cataracts, jaundice, hepatomeg, seizures

Galactosemia

Question 4

Uridyl diP galactose 4-epimerase def:

Answer 4

galactosemia + hypotonia, deafness

Question 5

Vit D def in exclusively BF baby:

Answer 5

• “ping pong” skull
• delayed fontanel closure
• enlarged skull/wrist/costochondral joints
• genu varum

Question 6

Endocarditis + new cond AV block =

Answer 6

perivalvular abscess

Question 7

Drug-induced esophagitis is a/w…

Answer 7

tetracycline, tylenol, NSAIDs, alendronate, KCl, quinidine, Fe

Question 8

Tx complicated diverticulitis w/ abscess?

Answer 8

CT-guided percutaneous drainage

Question 9

Causes of papillary necrosis:

Answer 9

long term NSAIDs
SCD
analgesic abuse
inf (pyelo)
DM

Question 10

s/e methimazole:

Answer 10

agranulocytosis, 1st tri teratogen, cholestasis

Question 11

s/e PTU:

Answer 11

agranulocytosis, hepatic failure, ANCA-asstd vasculitis

Question 12

Transposition of great vessels XR? Murmur?

Answer 12

egg on a string

single S2

Question 13

Tetrology of Fallot murmur? XR?

Answer 13

harsh pulm stenosis murmur, VSD

boot-shaped heart

Question 14

Tricuspid atresia murmur?

Answer 14

single S2, VSD

**minimal pulm blood flow

Question 15

Truncus arteriosus murmur?

Answer 15

single S2, systolic ej murmur

**incr pulm blood flow –> edema

Question 16

Extraarticular s/s of ankylosing spondylitis:

Answer 16

ant uveitis 
IBD
AR
inflmm at tendon insertion sites
limited chest expansion

Question 17

Splenic abscess a/w:

organisms?

Answer 17

inf (i.e. endocarditis) w hematogenous spread, hemoglobinopathy, immunosuppression, IVDU, trauma

staph, strep, salmonella

*s/s inf, L CP w effusion, LUQ pain

Question 18

TTP pres?

pathophys?

Answer 18

hemolytic anemia, renal failure, neurologic s/s

ADAMTS-13 (accum vWF multimers + plt aggregation)

**tx = plasmapheresis

Question 19

Drugs a/w dig toxicity?

Answer 19

amiodarone, verapamil, quinidine, propafenone (decr dose of dig when adding)

*life threatening arrythmias, NV, abdp, conf, weaknes, color vision changes

Question 20

G6PD def findings:

Answer 20

Heinz bodies + hemolysis

Question 21

Cryoglobulinemia:
etiology?
presentation?

Answer 21

IgM against anti-HepC IgG –> vasculitis involving skin, kidney (MPGN), nerves, joints

Question 22

Cryoglobulinemia:
labs?
dx?

Answer 22

incr RF, decr complement, incr LFTs

kidney or skin biopsy

Question 23

Decr dystrophin?

Absent dystrophin?

Answer 23

Becker’s

Duchenne’s

Question 24

Neonatal conjunctivitis:
24h?
DOL 2-5?
DOL 5-14?

Answer 24

24h = silver nitrate

DOL 2-5 = gonococcal
(IV/IM ceftriaxone/cefotaxime)

DOL 5-14 = chlamydial
(PO erythromycin)

Question 25

ADAMSTS-13 is a/w...

Answer 25

TTP | tx TTP = plasmapheresis

Question 26

Lab abn a/w refeeding syndrome?

Answer 26

incr insulin = decr K, Mg, phos

Question 27

Tx type 4 RTA:

Answer 27

fludrocortisone

Question 28

s/s cor pulmonale?

Answer 28

DOE, fatigue, exertional syncope, angina

Question 29

drug a/w rash in mono?

Answer 29

amox

Question 30

Pres of Parvo B19 inf?

Answer 30

5th disease in kids (F, N, facial rash) symm arthralgia in hands, wrists, knees, feet

Question 31

dx meconium ileus? | tx?

Answer 31

XR gastrograffin enema (if no change, srx)

Question 32

Labs a/w poor prog in CHF?

Answer 32

decr Na, incr BNP, incr Cr