3

Question 1

Smoke inhalation is a/w ___ toxicity. Tx?

Answer 1

CN toxicity

sodium thiosulfate or *hydroxocobalamin

Question 2

Gilbert’s: enzyme? symptoms?

Answer 2

UDP glucuronyl transferase

malaise, abd p (fasting, stress, sickness, etc)

Question 3

Crigler Najjar type 1: symptoms? tx?

Answer 3

severe jaundice and bili encephalopathy (presents in infants)

transplant (curative)

**NO CHANGE with PHENOBARB

Question 4

Crigler Najjar type 2: symptoms? management?

Answer 4

milder jaundice without bili enceph

PHENOBARB –> decr bili

Question 5

Rotor’s: pathophys?

Answer 5

abn conj bili storage –> leakage into plasma

Question 6

Pathophys of ARDS:

Answer 6

impaired gas exchange, decr lung compliance, pulm HTN

Question 7

Tx Candida?

Answer 7

fluconazole

Question 8

Causes of aortic regurg:

Answer 8

1. abn valves (rheum F, bicuspid AV, myxomatous degen, ankylosing spond, FenPhen)
2. asc aorta or aortic root abn (HTN, syph, akyl spond, dissection, Ehlers-Danlos, Marfan, IBD)

Question 9

Infarct?
ataxic hemiparesis (weak in LE + ipsalat arm with leg incoordination)

Answer 9

lacunar infarct in ant limb of int capsule

Question 10

Infarct?

dysarthria + clumsy hand

Answer 10

lacunar infarct at basis pontis

Question 11

Infarct?

unilat numbness, paresthesia, hemisensory loss in face/trunk/arm/leg (pure sensory)

Answer 11

ventroposterolateral nucleus of thalamus

Question 12

Infarct?

unilateral motor deficit + dysarthria (pure motor)

Answer 12

lacunar infarct in post limb of int capsule

Question 13

cause of lacunar syndromes?

Answer 13

small vessel disease causes lipohyalinotic thickening of small vessels
*smoking, HTN, DM, HLD

Question 14

Aortic dissection murmur?

Answer 14

diastolic decrescendo murmur at R sternal border

Question 15

Effects of maternal pre-E on neonate?

Answer 15

IUGR, polycythemia

Question 16

CMV retinitis on fundoscopy?

Answer 16

painless; fluffy or granular retinal lesions near retinal vessels + hemorrhages

Question 17

HSV retinitis on PE? fundoscopy?

Answer 17

painful + progr to vision loss; rapidly progr bil necrotizing retinitis –> keratitis and conjunctivitis

widespread, pale peripheral lesions + central necrosis of retina

Question 18

Tx bacillary angiomatosis?

Answer 18

abx –> regression

Question 19

Hyatid cyst: organism? presentation?

Answer 19

Echinococcus

unilocular cystic lesion (liver, lung, bone, musc), eggshell calc on CT

Question 20

Deficits a/w ant shoulder dislocation:

Answer 20

damage to axillary n/a –> paralysis of deltoid and teres minor + sensory loss to lateral upper arm

Question 21

Choriocarcinoma = incr…

Answer 21

bHCG

Question 22

Teratoma = incr…

Answer 22

AFP or bHCG

Question 23

Legdig cell tumor = incr… and decr…

Answer 23

incr E (due to incr aromatase)
decr LH/FSH

**precocious puberty, gynecomastia

Question 24

Yolk sac tumor (endodermal sinus tumor) = incr…

Answer 24

AFP

Question 25

Tx endometritis?

Answer 25

clinda, gent *polymicrobial: G+, G-, aerobic, anaerobic

Question 26

MCA stroke =

Answer 26

- contralat somatosensory + motor (UE, LE, face) - conj eye deviation to side of infarct - homonymous hemianopsia - APHASIA w HEMINEGLECT

Question 27

ACA stroke =

Answer 27

- contralat somatosensory + motor (LE) - abulia (lack of will/initiative) + emotional disturbances - dyspraxia - urinary incont

Question 28

vertebrobasilar stroke =

Answer 28

- contralateral hemiplegia - ipsalateral CN - +/- ataxia

Question 29

tx myasthenic crisis?

Answer 29

1. intubate, hold pyridostigmine | 2. IVIG or plasmapheresis + CS