2 Flashcards
(9 cards)
pH of blood
7.4 + or - 0.05
Survival range: 6.8 - 7.8
What could blood acidosis result from?
Starvation
Uncontrolled diabetes
What could blood alkalosis result from?
Severe vomiting
Kidney disease
Sources of H+ ions during exercise
CO2 production
Lactate production
ATP breakdown
Factors contributing to exercise induced acid production
Exercise intensity
Exercise duration
Amount of muscle mass involved
First line of defence against pH change during intense exercise
Cellular buffer systems - bicarbonate, phosphate, and protein buffers
Second line of defence against pH change during intense exercise
Blood buffer systems - bicarbonate, phosphate, and protein buffers
Respiratory compensation
Mechanism by which plasma pH can be regulated by varying respiratory rate
Carbon dioxide transport reaction
CO2 + H2O ↔️ H+ + HCO3-
Enzyme - carbonic anhydrase
This reaction occurs in the RBC, but the bicarbonate is transported in the plasma