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Pharmacology > 2- ANS > Flashcards

2- ANS Flashcards

(49 cards)

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1
Q

Botulinum toxin is used in ?

A 
Blepharospasm 
Strabismus 
Hyperhidrosis 
Dystonia 
Cosmetics
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2
Q

The sphincter that contracts in response to parasympathetic activation ?

A

Lower esophageal sphincter

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3
Q

Use of Bethanechol ?

A

Ttt of ileus and urinary retention

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4
Q

Use of Methacholine ?

A

Diagnosis of bronchial hyperactivity

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5
Q

Use of Pilocarpine and Cevimeline ?

A

ttt of xerostomia and glaucoma

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6
Q

Use of Edrophonium ?

A

Diagnosis of myathenia gravis

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7
Q

Use of Physostigmine ?

A

ttt of glaucoma

Antidote in atropine overdose

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8
Q

Use of Neostigmine and Pyridostigmine ?

A

Ttt of
Ileus
Urine retention
Myasthenia gravis

Reversal of nondepolarizing NM blockers

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9
Q

Use of Donepezil and Rivastigmine ?

A

Ttt of Alzheimer disease

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10
Q

Drug used to regenerate AChE ?

A

Pralidoxime ( 2-PAM )

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11
Q

Drugs with anti muscarinic pharmacology ?

A 
1- antihistamines 
2- TCA 
3- antipsychotics 
4- quinidine 
5- amantadine 
6- meperidine
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12
Q

Use of scopolamine ?

A

Ttt of motion sickness

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13
Q

Use of Benztropine and Trihexphenidyl ?

A

Ttt of Parkinsonism and acute extrapyramidal symptoms induced by antipsychotics

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14
Q

Use of Oxybutynin ?

A

Ttt of overactive bladder ( urge incontinence )

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15
Q

Nicotinic receptor antagonists?

A

Hexamethonium

Mecamylamine

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16
Q

Example for alpha 1 agonist and its use ?

A

Phenylephrine

Nasal decongestant
Ophthalmologic use ( causes mydriasis without cycloplegia )
In hypotensive states

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17
Q

Examples for alpha 2 agonists ? Their use ?

A

Clonidine
Methyldopa

In mild to moderate hypertension

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18
Q

Example for non selective beta agonist ?

A

Isoproterenol

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19
Q

Example for selective beta 1 agonist ? Its use ?

A

Dobutamine

In CHF

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20
Q

Example for selective beta 2 agonists ? Their use ?

Study These Flashcards
A

Salmetrol , albuterol , terbutaline —> in asthma

Terbutaline —> in premature labour

21
Q

Examples for NE releasers ?

Study These Flashcards
A

Tyramine in red wine and cheese
Amphetamines as methylphenidate —> in narcolepsy and ADHD
Ephedrine —> cold medication

22
Q

Examples for NE reuptake inhibitors ?

23
Q

MOA - A present in ? Metabolizes what ?

Study These Flashcards
A

Liver

NE
5-HT
Tyramine

24
Q

MOA-B resent in ? Metabolizes what ?

Study These Flashcards
A

Brain

Dopamine

25
Non selective alpha blockers ?
Phentolamine ( competitive inhibitor ) | Phenoxybenzamine ( non competitive inhibitor )
26
Selective alpha 1 blockers examples ?
Prazosine Doxazosine Terazosine Tamsulosine
27
Selective alpha 2 blocker ? Its use ?
Mertazapine As antidepressant
28
Beta blockers that have ISA and don’t increase blood lipids ?
Acebutolol | Pindolol
29
Selective beta1 blockers ?
Acebutolol Atenolol Metoprolol
30
Beta blocker that doesnot have sedation effect ?
Atenolol
31
Examples for drugs that have combined alpha 1 and beta blocking activity ? Their use ?
Carvedilol —> CHF | Labetalol —> hypertensive emergencies
32
Drug that have K channel blockade and beta blocking activity ?
Sotalol
33
Example for alpha 1 agonist and its use ?
Phenylephrine Nasal decongestant Ophthalmologic use ( causes mydriasis without cycloplegia ) In hypotensive states
34
Examples for alpha 2 agonists ? Their use ?
Clonidine Methyldopa In mild to moderate hypertension
35
Example for non selective beta agonist ?
Isoproterenol
36
Example for selective beta 1 agonist ? Its use ?
Dobutamine In CHF
37
Example for selective beta 2 agonists ? Their use ?
Salmetrol , albuterol , terbutaline —> in asthma Terbutaline —> in premature labour
38
Examples for NE releasers ?
Tyramine in red wine and cheese Amphetamines as methylphenidate —> in narcolepsy and ADHD Ephedrine —> cold medication
39
Examples for NE reuptake inhibitors ?
Cocaine | TCA
40
MOA - A present in ? Metabolizes what ?
Liver NE 5-HT Tyramine
41
MOA-B resent in ? Metabolizes what ?
Brain Dopamine
42
Non selective alpha blockers ?
Phentolamine ( competitive inhibitor ) | Phenoxybenzamine ( non competitive inhibitor )
43
Selective alpha 1 blockers examples ?
Prazosine Doxazosine Terazosine Tamsulosine
44
Selective alpha 2 blocker ? Its use ?
Mertazapine As antidepressant
45
Beta blockers that have ISA and don’t increase blood lipids ?
Acebutolol | Pindolol
46
Selective beta1 blockers ?
Acebutolol Atenolol Metoprolol
47
Beta blocker that doesnot have sedation effect ?
Atenolol
48
Examples for drugs that have combined alpha 1 and beta blocking activity ? Their use ?
Carvedilol —> CHF | Labetalol —> hypertensive emergencies
49
Drug that have K channel blockade and beta blocking activity ?
Sotalol

Pharmacology (9 decks)

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