2014 physiology Flashcards

1
Q
What is the major source of calcium for smooth muscle contraction?
A) Sarcoplasmic reticulum
B) Extracellular fluid
C) T-tubules
D) Mitochondria
A

A) Sarcoplasmic reticulum

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2
Q

What occurs when the body set point rises?
A) Shivering
B) Sweating
C) Vasodilatation

A

A) Shivering

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3
Q

What is the major reason for decreased neurotransmitter release from the presynaptic membrane into the synapse?
A) Increase in the amplitude of the action potential
B) Large amount of extracellular calcium
C) Binding of the neurotransmitter to receptors on the presynaptic membrane
D) Less releasable NT from vesicles

A

C) Binding of the neurotransmitter to receptors on the presynaptic membrane

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4
Q

An anemic patient has a cardiac output of 6.5, after restoring his level of hemoglobin back to normal, his systemic vascular resistance increased by 30%, what is his CO now (given that the difference in the pressure is constant)?
Blood flow = 6.5 L/min
Resistance increased by 30%
What’s the new blood flow if pressure is constant?
A) 4.5
B) 4.7
C) 5.0

A

C) 5.0

BF = CO
CO = diff in pressure/R 
CO1/CO2=R2/R1 so assuming R1= 1
Then R2 = 1.3 (coz R2 = 30% more than R1)
CO2 = 6.5 x 1/1.3 = 5
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5
Q

The binding of prolactin activates which of the following pathways?
A) Jak/Stat
B) cAMP/PKA/CREB
C) TGFB/SMAD

A

A) Jak/Stat

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6
Q

A patient was tested for the level of leptin in his blood and it showed to be 31.72, while the normal range of leptin is 5-7 leptin what is the reason behind this increase?
A) Excessive obesity
B) Eating a heavy fat meal
C) lack of exercise

A

A) Excessive obesity

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7
Q
A person went hiking to a mountain he was Non-acclimatized after he reached a high altitude he suffered from acid base disorder, which acid base disorder is most likely to occur? 
A) respiratory acidosis
B) metabolic alkalosis 
C) metabolic acidosis  
D) respiratory alkalosis
A

D) respiratory alkalosis

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8
Q

what is the cause of intracellular edema?
A) Na-k ATPase not functioning
B) closed K+ channels

A

A) Na-k ATPase not functioning

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9
Q

What is true about autonomic reflex?
A) monosynaptic
B) ganglionic relay

A

B) ganglionic relay

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10
Q

What type of contraction that doesn’t cause a change in muscle length?
A) Isometric
B) Isotonic
C) Eccentric

A

A) Isometric

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11
Q
Inside the cell there is a concentration of 9mM Chloride and outside the concentration of chloride is 90mM, what is the potential inside the cell?
A) -61
B) +61 
C) -90 
D)+ 90
A

A) -61

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12
Q
A solute is transferred through the membrane without using external energy, this process continues until the concentration in the cell reaches a critical level, this process is saturated afterwards. What is this process termed?
A) Simple diffusion 
B) Facilitated diffusion
C) Primary active transport 
D) secondary active transport
A

B) Facilitated diffusion

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13
Q

which of the following has the Highest oxygen concentration?
A) 21% oxygen at barometric pressure
B) 100% oxygen at barometric pressure
C) Blood with 21% oxygen at barometric pressure
D) Blood with 100% oxygen at barometric pressure

A

D) Blood with 100% oxygen at barometric pressure

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14
Q

What is true about a person who has adapted to a hot environment?
A) increase heat loss by evaporation
B) he starts sweating at a higher temperature than a non-adapted person
C) Increase of salts excretion in the sweat

A

A) increase heat loss by evaporation

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15
Q

What is a cell adhesion molecule?

A

Integrin

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16
Q

What is the state of voltage-gated Na channel if it’s clumped at +10 mV?
A) activation gate open, inactivation closed
B) activation gate open, inactivation open

A

A) activation gate open, inactivation closed

17
Q

What domain of myosin I binds the membrane?
A) motor domain
B) nucleotide binding pocket
C) TH1

A

C) TH1

TH1 binds fat

18
Q

A person consumes 200 ml/min oxygen and produces 162.5 ml/min of CO2. Which of the following is true about his diet?
A) it is a typical mixed diet
B) high fat diet
C) high carbs diet

A

A) it is a typical mixed diet

19
Q

What is the last step of endocytosis?
A) binding of the substance to the receptor on the cell surface
B) Dissolving clathrin
C) Dimerization of dynamin

A

B) Dissolving clathrin

20
Q

A person voluntarily stopped breathing for a short period of time resulting in an accumulation of CO2. After checking his blood pH, it was within the normal range and it didn’t change much. What is the reason behind this minimal change in his pH?
A) Hemoglobin
B) Bicarbonate

A

A) Hemoglobin

21
Q

which of the following cations is the major one in the extracellular compartment?
A) K
B) Na
C) Mg

A

B) Na

22
Q

Which of the following provides mechanical strength and supports shape and nucleus?
A) Intermediate filaments
B) microtubules
C) microfilaments

A

A) Intermediate filaments