2018 MCQ Flashcards
(124 cards)
66 yo M presents to ED w/ angina pectoris. Admin med. which acts by releasing NO and his sx.s are relived. What is the most likely med?
GTN
twin-twin transfusion syndrome
Diagnosis requires 2 criteria
1. the presence of a MCDA pregnancy
2. presence of oligohydramnios (defined as a maximal vertical pocket of <2cm) in one sac AND of polyhydramnios (max. vertical pocket of >8cm) in the other sac
MCDA pregnancy
Monochorionic, diamniotic (MCDA)
- product of single fertilised egg= genetically identical twins
- share single placenta (Blood supply) but have separate amniotic sac
- Which of the following drugs is most likely to reduce mortality and morbidity in patients
with either diastolic or isolated systolic hypertension?
A. Calcium blockers
B. Thiazide-like diuretics
C. Alpha blockers
D. ACE inhibitors
E. Beta blockers
B
- note sure why answer isn’t CCB
- compared to CCBs or thiazide diuretics, ACEi/ ARBs have distinctly less efficacy in patients w/ isolated systolic HTN
Why is carbidopa used in the Tx of parkinson’s
Levodopa is converted to dopamine in the brain and peripheral tissue and replenishes the depleted striatal dopamine. It is given w/….
Carbidopa (or benserazide)= peripheral dopa decarboxylase inhibitor: To reduce the metabolism of L-Dopa in the periphery.
And therefore reduce production of dopamine in the periphery and also reduce adverse effects (e.g. nausea, vomiting, hypotension)
autograft, allograft, isograft, xenograft, technograft
Autograft: transplant to self from self
AllograftL transplant between genetically different ppl
IsograftL transplant btw genetically identical people
Xenograft: transplant btw different species
A previously well 14 month-old child, presents with a history of sudden onset of cough
and wheeze. He was playing with some toys earlier. On examination, there is evidence of
reduced air entry and wheeze over the right lung. Which of the following is the most likely
diagnosis?
A. Asthma
B. Bronchiolitis
C. Congenital airway abnormality
D. Inhaled foreign body
E. Pneumonia
D
Woman presents 10 weeks pregnant and gets a FBC, it shows a microcytic anaemia
and the blood film showed thalassemia B traits. The blood status of the partner is
unknown. What is the management?
Prevention of B thalassaemia major include:
- genetic counselling or antenatal diagnosis using fetal blood or DNA then ‘therapeutic’ abortion
28yo male with acute psychosis was admitted to the psychiatric ward for treatment for
10 days. Experienced sudden intense painful neck muscle cramping/stiffness and a
forward flexion of head. What is the drug that most likely caused his symptoms?
A. Benztropine
B. Fluoxetine
C. Haloperidol
D. Lithium
E. Olanzapine
and why
Haloperidol
- the pt has torticollis (dystonic EPSE)
-typical antipsychotics like haloperidol have more EPSEs than atypical e.g. olanzapine
what is it
pilonidal cyst (discomfort when sitting down, 23yo M)
35 y/o male feels anxious, gets tingling sensation in the lips (and other Sx) in certain
situations. He is worried to have these symptoms in front of others, therefore he avoids
crowded places. He is soon to be promoted to a higher position at work and wasn’t sure if
he could cope with it.
A. Generalised Anxiety Disorder
B. Panic Disorder
C. Social Phobia
D. Post-traumatic disorder
E. Depression
C
MoA donepezil
main therapeutic use is in alzheimer’s to increase cortical acetylcholine (acetylcholinesterase inhibitors)
30y/o lady, G2P2, comes in with 6 week old son for routine appointment. Has
symptoms of poor concentration, sleep, fatigue, loss of weight to below pre-pregnancy
weight. Vehemently denies being depressed, didn’t feel that way with first child. What is
the diagnosis?
A. Post natal depression
B. Post natal psychosis
C. Adjustment disorder
D. Baby blues
E. Persistent depressive disorder
A
23 year old married woman presents with vaginal discharge/pain. Dysuria but no
pruritus. On examination she has a raised painful inguinal lymph nodes with red ulcers on
both vulva and the cervix appears red and ulcerated. There is no malodour but profuse
clear discharge. Diagnosis?
Herpes genitalia
- genital herpes presents w/ panful genital ulcers vs primary syphilis presents w. painLESS ulcers (chancre)
7yo well, asymptomatic girl has loud pansystolic murmur, palpable thrill at left sternal
edge. Routine check. Heart sounds and apex beat otherwise normal. Diagnosis?
Ventricular septal defect (VSD)
- harsh pansystolic murmur at LSE w/ systolic thrill +/- L parasternal heave
19 yo male comes to GP very distressed. Worried about his nose, think’s it’s big and is
very conscious of it and wants to get plastic surgery because he looks at it in the mirror all
the time and he thinks the girls won’t like him because of it.
A. Body dysmorphic disorder
B. Delusional disorder
C. Micropenis
D. OCD
E. Congenital nasal hypertrophy
A
80 Year old female presents with sudden vision loss in left eye one hour ago. Over the
past week she has been having pain in her jaw when she chews. O/E she has tender,
enlarged superficial temporal arteries. What is the most appropriate immediate
management?
A. Temporal artery biopsy
B. Thombolytic therapy
C. Commence steroids
D. Cerebral angiogram
E. Urgent referral to ophthalmologist
C
GCA: start prednisolone 60mg/day PO immediately and do temporal aa bx w/in 14 days of starting steroids
20yo man brought into ED by housemates. Has rapid speech but could be interrupted.
Thought the Prime Minister was a robot sent from the future, like terminator, to kill him and
then destroy the human race. Diagnosis?
A. Mengele alogia
B. Grandiose Delusion
C. Persecutory delusion
D. Formal thought disorder
E. Projection
C
Young boy presented with sudden testicular pain. Felt nauseous and vomited.
Diagnosis?
A. Epididymitis
B. Testicular torsion
C. Hydrocoele
D. Varicocele
B
sudden onset of pain in ONE testis: makes walking uncomfortable
pain in abdo, n+v
28yo male presented with firm, non-tender intratesticular lump that is hypoechoic on
ultrasound. What do you do to confirm the diagnosis?
A. Inguinal orchiectomy
B. Trans-scrotal open biopsy
C. Trans-scrotal core biopsy
D. Fine needle aspirate
E. Serum B-HCG
why
A
when testicular cancer is suspected entire testicle is removed (orchiectomy)
testicular bx is NOT performed as a a part of evaluation due to concern that it may result in tumour seeding into the scrotal sac or mt.s into inguinal nodes
Pregnant woman completed first stage of labour in 7 hours, and second stage in 3
hours. She is well. What medication does she need now?
A. Syntocinon 10U IM
B. Syntocinon IV infusion
C. Ergometrine
syntocinon 10U IM
3rd stage of labour interventions
-The use of uterotonics are recommended for ALL births to prevent PPH (post partum haemorrhage)
-oxytocin 10IU IV/IM is recommended
35y/o female presented with a 2 year history of a slowly enlarging lump on her neck,
the mass is mobile and non tender, on the left side of her neck. She is euthyroid and
asymptomatic. Likely diagnosis is:
A. Hashimoto’s
B. Thyroid cancer
C. Simple thyroid cyst
D. Thyroid adenoma
E. Toxic multinodular goitre
simple thyroid cyst
A 30yo pregnant woman presents with premature rupture of membranes at 32 weeks.
She needs transfer to a more established hospital. In the meantime, what medications
should you give her?
vancomycin + flucloxacillin
9-month-old infant female presents distressed with proteins +++, nitrites +, leukocytes
+ on urine dipstick. She is febrile 38°C. What is the next single best step?
A. Renal USS
B. Cephalexin TDS
C. Wait until MCS to give antibiotics
D. Renal biopsy
B