2022 Flashcards

1
Q

for which RNA virus, initially encountered in the gastrointestinal tract, is a vaccine not available

A

norovirus

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2
Q

which virus is the most common agent of gastroenteritis in children

A

rotavirus

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3
Q

similar to 2023
what HIV protein binds to CD4 on host cell surface

A

gp120

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4
Q

what is the main reason that HIV positive individuals are able to transmit the virus many years after their initial infection

A

viral DNA integrated in the host genome is transcribed by host cell RNA polymerase II

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5
Q

what are the characteristics of adenovirus

A

double-stranded DNA genome, naked capsid

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6
Q

what is the role of the human papillomavirus E6 protein during infection

A

binds p53 and promotes p53 degradation

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7
Q

which hepatitis virus causes a high incidence of persistent infections (70% of infections becoming persistent in otherwise healthy adults)

A

HCV

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8
Q

which of the following is characteristic of infection with hepatitis B virus

A

dane particles

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9
Q

what condition, caused by a virus, results in vesicles confined to the fingers and used to be more common among dentists

A

herpetic whitlow

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10
Q

which of the following is a diagnostic for infection with herpes simplex virus type 1

A

cowdry type A inclusion bodies

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11
Q

what is the cause of shingles

A

varicella zoster virus reactivation

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12
Q

a individual who has been vaccinated against HBV would display which of the follow serological properties

A

presence of anti-HB antibodies combined with absence of all HB antigens

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13
Q

which virus genome is directly translated into proteins upon early entry into a cell

A

hepatitis A virus

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14
Q

which class of anti-HIV drug is also effective against hepatitis B virus

A

reverse transcriptase inhibitors

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15
Q

enfuvirtide is an HIV fusion inhibitor that

A

binds to gp41

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16
Q

which of the following is not a use of passive immunization

A

to create long-lived immunity

17
Q

what is true about the new COVID-19 vaccine released by Novavax in july 2022

A

it contains viral spike protein segments

18
Q

what disease is caused by the conversion of the normal PrPC protein to the PRP Scrapie form

A

creuzfeldt-Jakob disease

19
Q

some drugs for treating influenza virus infections block release of new virus from the surface of patients’ infected cells by

A

inhibiting viral neuraminidase

20
Q

what anti-fungal class binds ergosterol in fungal membranes and alters membrane permeability

21
Q

which is a characteristic component of most fungal cell walls

A

polymer of N-acetyl-glucosamine

(NOT N-acetyl-muramic acid polymer)

22
Q

which form of candidiasis is typically associated with the oral mucosal surfaces on which dentures sit

A

chronic erythematous

23
Q

which fungus lacks a yeast form, only exhibiting a mold form

A

aspergillus fumigatus

24
Q

which of the following is associated with coccidioides immitis

A

chronic meningitis

25
what protozoan is chlorine-resistant, making it easy to transmit in public swimming pools
cryptosporidium parvum
26
what agent causes periodic attacks of chills and fever that coincide with massive lysis of red blood cells
plasmodium falciparum
27
what pathogen does not cause a diarrheal disease
toxoplasma gondii
28
eosin methylene Blue agar (EMB) is an example of which type of culture medium used for diagnosis of a bacterial infection
differential medium
29
what is true about a direct ELISA assay detecting specific antibodies in patient serum
there are antibodies from the patient's serum above a layer of specific antigen bound to the solid support
30
what is true about mechanical transmission with respect to vector-borne pathogens
the pathogen is carried externally on the body of the vector (passively)
31
when considering a propagated epidemic of an infectious disease, what is the minimum number of susceptible individuals necessary to continue propagating the disease
threshold density