Flashcards in 20.5 gene expression and cancer Deck (19):
compare the size of a benign tumour to a malignant tumour
both grow to a large size
compare the speed to growth in a benign tumour to a malignant tumour
benign-> grows slowly
malignant-> grows quickly
compare the state of differentiation in benign tumours to malignant tumours
what is metastasis?
process where tumours spread to other parts of the body forming secondary tumours
compare the adhesion of the cells in benign tumours and malignant tumours
benign-> adhesion molecule produced so stick together
malignant-> no adhesion molecules so don't stick together
compare the presence of a capsule in benign tumours and malignant tumours
malignant-> no capsule
compare the threat to life benign tumours and malignant tumours have
benign-> not life threatening
malignant-> life threatening
compare the effect of the body benign and malignant tumours have
how are benign tumours removed?
how are malignant tumours removed?
radiotherapy, chemotherapy, surgery
compare how frequent benign tumours and malignant tumours appear after treatment
malignant-> more frequently
malignant tumour definition
benign tumour definition
non- cancerous tumour
what are the 2 main type of genes that play a role in cancer?
- tumour suppressor genes
what are oncogenes?
what are proto-oncogenes?
genes that stimulate a cell to divide when growth factors attach to a protein cells on its cell surface membrane
what happens to proto- oncogenes when growth factors attach to them?
genes are activated which cause DNA to replicate and the cell divides
why are oncogenes genes permanently switched on?
- receptor protein can be permanently activated, so that cell division is switched on even if the growth factor is absent
- oncogenes code for a growth factor that is then produced in excessive amounts causing excessive division of cells