Neurotransmitters -- First Aid

Question 1

Norepinephrine (NE)

Answer 1

Diseased state = increased anxiety, decrease in depression

Synthesis = locus ceruleus (pons) – stress and panic

Question 2

Dopamine (DA)

Answer 2

Diseased state = increased in Huntingtons, decreased in Parkinson’s, decreased in depression

Synthesis = ventral tegmentum and SNc (midbrain)

Question 3

5-HT (serotonin)

Answer 3

Diseased state = increased in Parkinson’s, decreased in anxiety, decreased in depression

Synthesis = Raphe nucleus (pons, medulla, midbrain)

Question 4

ACh

Answer 4

Diseased state = increased in Parkinson’s, decreased in AD, decreased in Huntington’s

Synthesis = Basal nucleus of Meynert

Question 5

GABA

Answer 5

Diseased state = decreased in anxiety, decreased in Huntington disease

Synthesis = nucleus accumbens (reward center, pleasure, addiction, fear)