21 - anatomy and function of the heart Flashcards

(42 cards)

1
Q

what does the systematic system do?

A

controls blood flow to and from the body.

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2
Q

what does the pulmonic system do?

A

controls blood flow to and from the lungs.

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3
Q

what are vessels that carry blood away from the heart know as?

A

arteries

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4
Q

what are vessels that carry blood towards the heart known as?

A

veins

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5
Q

what do capillaries do?

A

permit exchange of gasses and waste.

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6
Q

describe systemic circulation

A

originated blood is cycled from the left side of the heart to the rest of the body. gas exchange takes place and the blood becomes de-oxygenated which gets cycled from the body to the right side of the heart.

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7
Q

describe pulmonic circulation

A

de-oxygenated blood is cycled from the right side of the heart to the lungs. gas exchange takes place and the blood becomes oxygenated which gets cycled back from the lungs to the left side of the heart.

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8
Q

what are the major arteries?

A
  • right pulmonary arteries
  • left pulmonary arteries
  • aorta
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9
Q

what are the major veins?

A
  • superior vena cava
  • inferior vena cave
  • right pulmonary veins
  • left pulmonary veins
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10
Q

what is the pericardium?

A

fibrous pericardium, serous pericardium, pericardial fluid.

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11
Q

what are the three layers of the wall of the heart?

A
  • epicardium
  • myocardium
  • endocardium
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12
Q

what are coronary vessels?

A

coronary arteries and cardiac veins

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13
Q

what does the pericardium do?

A

it is a double layered membranous sac surrounding the heart.

  • protects the heard from infection
  • lubricated the heart (serous or pericardial fluid)
  • stabilises the heart (limits the heart from becoming too large, anchors the heart within the thoracic cavity to prevent it fro moving)
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14
Q

what are the layers of the pericardium?

A

outer - fibrous pericardium
inner - serous pericardium

  • parietal pericardium
  • pericardial fluid
  • visceral pericardium/epicardium
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15
Q

what is the epicardium?

A
  • Visceral pericardium covering the heart
  • Exposed mesothelium (single squamous epithelial layer)
  • Loose connective tissue that attached to myocardium
    Serves as an additional layer of protection to the heart
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16
Q

what is myocardium?

A
  • Thickest layer
  • Lies between the epicardium and endocardium
  • Striated muscle (like skeletal muscle), made from cells known as myocytes. These cells are shorted than skeletal muscle cells
  • Myocytes are formed of several fibres known as myofibrils
  • Involuntary contracts the wall of the heart. Through the autonomic nervous system.
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17
Q

what are myocytes?

A
  • bundles of myofibrils
  • often single nucleus
  • sarcolemma
  • sarcomeres actin (thin filament) and Myosin (thick filament)
18
Q

what do gap junctions do?

A

allow the transport of ions between calls and enables quick transmission of action potentials.

19
Q

what do desmosomes do?

A

anchors ends of muscles fibres together so they don’t pull apart during contraction.

20
Q

how do muscles contract?

A
  • Action potential triggers release of calcium ions, Ca+ released from sarcoplasmic reticulum
  • Actin filaments bond to myosin filament
  • Z-discs/lines move closer together
  • Muscle contract
21
Q

how do muscles relax?

A
  • Calcium ions reabsorbed
  • Actin filaments blocked from binding to myosin
  • Muscle relaxes
22
Q

what is endocardium?

A

lines the heart chambers and heart valves

23
Q

what is endothelium?

A
  • Inner layer of blood vessel (also lined lymphatic vessels)
  • Controls vascular tone and motion/formation of new blood vessels
  • Controls the migration of white blood cells which defend the body against infection.
24
Q

what can a blocked coronary artery lead to?

A

a heart attack

25
what does the aorta do?
- Transports oxygenated blood away from the left ventricle in the heart to the rest of the body - Blood first flows from the left ventricle to the ascending aorta - The aortic arch branched into the carotid and subclavian arteries and transports blood to the upper parts of the body - The descending aorta transports blood to the lower regions of the body.
26
what does the pulmonary artery do?
- Transports deoxygenated blood away from the right ventricle in the heart to the lungs - Blood first flows into the pulmonary trunk which branches into the right and left pulmonary arteries
27
what do the superior and inferior vena cava do?
- Transports deoxygenated blood to the right atrium of the heart, from the rest of the body - Superior vena cava transports blood from the upper body - Inferior vena cava transports blood from the lower body
28
what do pulmonary veins do?
- Transports oxygenated blood to the left atrium in the heart, from the lungs - 4 branches: 2 right and 2 left pulmonary veins
29
what are the valves of the heart?
Semi-lunar valves - Aortic value - controls flow of blood from ventricle to rest of body - Pulmonary valve - controls flow of blood right ventricle to lungs Atrio-ventricular valves - Mitral valve - controls flow of blood from atrium to left ventricle - Tri-cuspid valve - controls flow of blood right atrium to right ventricle
30
describe the aortic valve
Sits at the base of the aortic root 3 leaflets (or cusps) - Left coronary artery - Right coronary artery - Non-coronary artery Coronary ostium - To right and left coronary arteries - Allows blood to flow to the heart muscle Aortic sinus - Facilitates closure of the valve
31
describe the mitral valve
Called 'mitral' because its shaped like a mitral (a bishops hat) 2 leaflets - Anterior leaflet - Posterior leaflet Papillary muscles and chordae tendineae - Pulls the leaflets to prevent them inverting into the atrium.
32
explain the cardiac conduction system
The heart has its own pacemaker known as the sinoatrial mode (SA node) which controls the contraction of the muscle fibres. The SA node consists of a group of specialised muscle cells which spontaneously depolarise. The conductions travels as follows: - The SA node - located in the wall of the right atrium - Internodal pathways atrioventricular node (AV node) - located in the atrium and ventricular junction - Bundle of HIS - Left and right bundle branch (RBB and LBB) - Purkinje fibres
33
explain atrial and ventricular diastole
- Blood returning to the right atrium is known as venous return - Pressure in atria exceeds pressure in ventricles - Atrioventricular valves open - Ventricles passively fill with blood from atria - 90% of total ventricular filling - Aortic and pulmonary pressures fall - Pressure difference between atria and ventricles decreases - This leads to a decrease in rate of filling
34
explain atria systole & ventricular diastole
- Atria contracts - Final 10% of ventricular filling. Ventricular filling at a maximum (typically 120 ml) - End diastolic volume (EDV) - Pressure in ventricles exceed atrium - Atrioventricular valved close - The degree of ventricular stretching is known as preload, the greater the tension produced by the ventricles.
35
what is iso-volumetric contraction?
- All valves closed - Ventricles begin to contract - Iso-volumetric contraction - as there is no change in volume in the ventricles - Pressure in ventricles rises sharply
36
what is ventricular systole?
- Pressure in ventricle exceed that of arteries - Semi-lunar valves open - Blood is ejected rapidly to the aorta and pulmonary arteries - The amount of blood ejected into the arteries from the ventricles is known as stroke volume. Its approximately 70 ml - The cardiac output is the stroke volume per minute for the left ventricle
37
what is ejection fraction?
percentage ratio of stroke volume to end diagnostic volume.
38
what is iso-volumetric relaxation?
- As ventricle empties, the pressure drops below that of the arteries - All valves close - Ventricles and atria relax - Blood remaining in ventricles at end of systole is called the end systolic volume (ESV)
39
how is heart rate adjusted through dual innervation of the sympathetic and parasympathetic fibres?
- Sympathetic innervation - norepinephrine released to accelerate the heart rate - Parasympathetic innervation - acetylcholine released to slow down the heart rate - SA node, AV node and atrial muscle cells innervated equally - Ventricular muscles cells innervated more by sympathetic fibres
40
what do circulating hormones such as epinephrine do?
control the rate of spontaneous depolarisation of the SA node and repolarisation period
41
explain venous return
an increase in the venous return. De-oxygenated blood returning to the right atrium will stretch the muscles fibres of the SA node more which leads to more rapid depolarisation --> increased heart rate.
42
what things effect stoke volume?
End diastolic volume (EDV) Affected by two things: filling time and venous return (preload) Filling time Affected by the heart rate - A decreased heart rate increased ventricular filling time - A faster heart rate leaves little time for filling Preload - Increased venous return increases the end diastolic volume which increases the stretching of the ventricular walls --> a higher preload --> increased force of contraction End systolic volume (ESV) Affected by three things: preload, contractility and afterload. Contractility (inotropy) - Sympathetic - positive inotropy – increase of calcium ion uptake by cardiac muscle fibres in the ventricle → increased force of contraction → decreased ESV→ increased stroke volume. - Parasympathetic – negative isotropy – inhibition of calcium ion uptake by cardiac muscle fibres in the ventricle → decreased force of contraction → increased ESV → decreased stroke volume. Afterload - Tension produced by the ventricles to overcome the pressure in the arteries and open the semi-lunar valves. - Increases with increased pressure in aorta. Greater the afterload → longer the period of iso-volumetric contraction → increased ESV → decreased stroke volume.