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MTAP hematology Part 2 (Platelets > 2.1 Primary hemostasis > Flashcards

2.1 Primary hemostasis Flashcards

1
Q

Platelets originate from polyploid _____________ the largest of all hematopoietic cells which account for less than 0.5% of the total nucleated marrow cells

A

Megakaryocytes

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2
Q

Megakaryocyte proliferation is largely regulated by?

A

Thrombopoietin

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3
Q

Thrombopoietin primary sours is in the what organ?

A

Liver

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4
Q

Plasma concentration is _______________ to platelet count

A

Inversely proportional

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5
Q

TPO is ________________ to Platelet count

A

Inversely proportional

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6
Q

Megakaryocyte development is characterized by?

A

Endomitosis

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7
Q

Form of mitosis unique to Megakaryocytes in which DNA replication and cytoplasmic maturation are normal but cells lose their capacity to divide

A

Endomitosis

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8
Q

In endomitosis, lobules of nucleus being divided instead of the cells

T or F

A

T

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9
Q

Nucleus: Round

a. MK I
b. MK II
c. MK III

A

a

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10
Q

Nucleus: Indented

a. MK I
b. MK II
c. MK III

A

b

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11
Q

Nucleus: Multilobed

a. MK I
b. MK II
c. MK III

A

c

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12
Q

Also known as promegakaryocytes

a. MK I
b. MK II
c. MK III

A

b

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13
Q

Also known as Megakaryoblast

a. MK I
b. MK II
c. MK III

A

a

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14
Q

Also known as Megakaryocyte

a. MK I
b. MK II
c. MK III

A

c

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15
Q

Nucleoli: Not visible

a. MK I
b. MK II
c. MK III

A

c

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16
Q

Nucleoli: Variable

a. MK I
b. MK II
c. MK III

A

b

17
Q

Nucleoli: 2-6

a. MK I
b. MK II
c. MK III

A

a

18
Q

Chromatin: Homogeneous

a. MK I
b. MK II
c. MK III

A

a

19
Q

Chromatin: Deeply, variably condensed

a. MK I
b. MK II
c. MK III

A

c

20
Q

Chromatin: Moderately condensed

a. MK I
b. MK II
c. MK III

A

b

21
Q

N:C: 3:1

a. MK I
b. MK II
c. MK III

A

a

22
Q

N:C: 1:2

a. MK I
b. MK II
c. MK III

A

b

23
Q

N:C: 1:4

a. MK I
b. MK II
c. MK III

A

c

24
Q

Mitosis: Absent

a. MK I
b. MK II
c. MK III

A

abc

25
Q

Endomitosis: Present

a. MK I
b. MK II
c. MK III

A

a

26
Q

Endomitosis: Ends

a. MK I
b. MK II
c. MK III

A

b

27
Q

Endomitosis: Absent

a. MK I
b. MK II
c. MK III

A

c

28
Q

Cytoplasm: Basophilic

a. MK I
b. MK II
c. MK III

A

a

29
Q

Cytoplasm: Basophilic, granular

a. MK I
b. MK II
c. MK III

A

b

30
Q

Cytoplasm: Azurophilic, granular

a. MK I
b. MK II
c. MK III

A

c

31
Q

Granules, DMS: PResent

a. MK I
b. MK II
c. MK III

A

abc

MTAP hematology Part 2 (Platelets (20 decks)

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