Magnesium Sulfate

Question 0

Mechanism of Action

Answer 0

2nd most plentiful intracellular cation, decreases myocardial irritability and neuromuscular irritability.

Question 1

Class

Answer 1

Electrolyte, tocolytic

Question 2

Indications and Field Use

Answer 2

Torsades de Pointes, VF/Pulseless VT refractory to lidocaine and/or amiodarone.
Preterm labor
Pre-eclampsia, Eclampsia
Reactive Upper Airway Disease-severe asthma

Question 3

Adverse Reactions

Answer 3

Hypotension, Respiratory depression and/or paralysis, Hypothermia

Question 4

Adult Dosage

Answer 4

VF/Pulseless VT: 1-2gm IV diluted in 50-100mL NS or D5W administered over 1-2 minutes
TDP: 1-2gm IV diluted in 50-100mL NS or D5W administered over 1-2 min followed by infusion over 1 hour
Preterm Labor: 4-6grams over 15-20 minutes.
Eclampsia: 3-6grams over 10-15minutes