Addiction Flashcards
1
Q
What drugs increase DA in the nucleus accumbens?
A
Nicotine, alcohol, opiates, cocaine
2
Q
Some factors that increase propensity towards addiction
A
- Heredity
- ->Dose, flushing, pleasant effect, rapidity of tolerance
- Rapidity of tolerance
- Metabolism
- Amt of reward
- Psychiatric disorders (self medication)
3
Q
Drug’s effects on D2 receptors
A
They decrease them (tolerance). When you’re clean for 4 mo, start to come back…don’t revert to normal right away
4
Q
D2 effects on drugs
A
People with high D2 levels had an unpleasant response to stimulants. Low had a pleasant response
5
Q
What parts of the brain were activated with cocaine craving?
A
Anterior cingulate and the amygdala
