carcinogens and their cancers Flashcards

1
Q

aflatoxins

A

hepatocellular carcinoma - from aspergillus (rice and grains)

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2
Q

alkylating agents

A

leukemia lymphoma

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3
Q

alcohol

A

squamous cell carcinoma or oropharynx and upper esophagus and hepatocellular carcinoma

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4
Q

arsenic

A

squamous cell carcinoma of skin, lung cancer and angiosarcoma of the liver

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5
Q

asbestos

A

lung carcinoma and mesothelioma

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6
Q

cigarette smoke

A

carcinoma of oropharynx, esophagus, lung, kidney, bladder and pancreas

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7
Q

nitrosamines

A

stomach carcinoma ( smoked foods - japan)

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8
Q

naphthylamine

A

urothelial carcinoma of bladder ( from cig smoke)

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9
Q

vinyl chloride

A

angiosarcoma of liver ( pVC pipes)

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10
Q

nickle, chromium, beryllium, silica

A

lung carcinoma

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11
Q

EBV

A

nasopharyngeal carcinoma, burkitts, cns lymphoma in AIDS

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12
Q

HHV-8

A

kaposi sarcoma

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13
Q

HBV and HCV

A

hepatocellular carcinoma

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14
Q

HTLV-1

A

adult t cell leukemia/ lymphoma

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15
Q

high risk HPV (16, 18,31,33)

A

squamous cell carcinoma of vulva, vagina, anus, cervix and adenocarcinoma of cervix

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16
Q

ionizing radiation

A

AML, CML, papillary carcinoma of the thyroid ( bc hydroxyl free radicals)

17
Q

nonionizing radiation ( UVB )

A

basal cell carcinoma , squamous cell carcinoma, melanoma of the skin ( pyrimidine dimers - normally excised by restriction endonuclease)