23. Aujeszky’s disease (diagnosis, prevention, control, eradication). Flashcards Preview

Epidemiology final Topic (1-102) > 23. Aujeszky’s disease (diagnosis, prevention, control, eradication). > Flashcards

Flashcards in 23. Aujeszky’s disease (diagnosis, prevention, control, eradication). Deck (4)
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1
Q

Diagnosis?

A

Diagnosis:

  • history, clinical signs, virus isolation
  • (nasal discharge, brain, lung - CPE within 1-2 days),
  • from tissue (IF, IP, latent infections PCR, NS hybridization),
  • serology (VN, ELISA - discriminative, CF, AGID)
2
Q

Differential diagnosis?

A

Differential diagnosis:

  1. every CNS signs diseases,
  2. Teschen disease,
  3. classical swine fever
3
Q

Prevention?

A

Prevention:

  • reduce mixing animals,
  • separation of swine from other species,
  • don’t feed carnivores with raw pork and organs, immunization
  • Immunization: IgE negative marker vaccines, attenuated/inactivated, protection from 7-10 days
  • until 3-4 months
  • Basic immunization with attenuated live virus
  • 1st vaccination of maternally protected pigs on 10-12 weeks and repeat in 2 weeks
  • Gilts: vaccinations at the age of 6 months, at fertilization and at 70-90th day of pregnancy
  • Ruminants, carnivores: vaccine not reliable (attenuated can cause disease, inactivated will
  • not protect longterm)
4
Q

Eradication?

A

Eradication:

  • The virus can maintain in vaccinate pigs
  • Obligatory eradication ʹ national laws
  • Replacement ʹ (UK, Denmark) ʹ expensive
  • Raising virus-free generation: early weaning of pigs from vaccinated sows, isolated keeping,
  • serological testing
  • Selection with the help of marker vaccines
  • Immunisation of the whole herd with marker vaccine in every 4months
  • Regular checking with discriminative ELISA
  • Isolation ofthe different age-groups reduced virus shedding,slower spread
  • When the number of sero-positives are low, their removal from the herd
  • “Vaccinated virus free “animals serological monitoring (10%inevery 6months)+
  • testing of abortions, stillbirths
  • Ceasing vaccination ʹ becoming seronegative
  • Maintenance of the virus-free status
  • Epizootiological measures, import from free herds, quarantine
  • Regular serological monitoring (ELISA)

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