23 Genes and Development Flashcards
(25 cards)
dentricles
larval segments identified by the distribution of cuticular hairs
how do mRNAs from nurse cells know how to move
via microtubules
distribution of bicoid mRNA in egg
anterior
distribution of nanos mRNA in egg
posterior
mutations in bicoid and nanos
result in larva existing in opposite end
bicoid mutants have
two posterior ends
mutations in maternaal effect genes do not
follow mendelian patterns of inheritance
zygotic genes
genes that are transcribed after fertilization
kruppel
“gap” genes
maternal effect genes regulate
gap genes
gap genes regulate
“pair rule” genes, hairy
loss of hairy
deletion of alternate segments
loss of kruppel
deletion of middl segments
pair rule genes regulate
“segment polarity” genes like engrailed
loss of engrailed causes
mirror of posterior
hierarchy of gene regulation(5)
maternal effect
gap
pair-rule
segment polarity
proper segmentation
HOX genes
code for transcription factors that are expressed in an anterior-posterior pattern
HOX genes specify
identity of adult structures in particular segments
mutations in the Hox gene bithorax cause
3rd thoracic segment to adopt 2nd thoracic segment
combinatorial gene expression also
regulates plant developement
Pax6. loss of function mutations
result in organisms with abnormal eye development
why cant drosophilia produce a mouse eye and only a. fly eye
lack genes to do so
lateral inhibition example
vulval cellls in C. elegans
lateral inhibition
cells send. out signals to cells adjacent to prevent. differenciation
