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pharm 2 - final review > Anitmicrobials > Flashcards

Anitmicrobials Flashcards

1
Q

MOA inhibit folic acid synthesis

A

Sulphonamides

Diaminopyrimidines

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2
Q

MOA inhibit 50S ribosomal subunit

A

Macrolides
Lincomycin
Cholarmaphenical

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3
Q

MOA inhibit 30S ribosomal subunit

A

Aminoglycosides

Tetracyclines

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4
Q

MOA inhibit RNA synthesis

A

Rifampin

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5
Q

MOA inhibit DNA synthesis

A

Fluoroquinolones

Metronidazoles

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6
Q

MOA cell wall inhibitors

A

B- lactams (Pen, Cephalosporin, Cabapenems, Monobactams)
Bacitracin
Vancomycin
Cyclosporins

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7
Q

MOA cell membrane

A

Polymyxin B

Colistin

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8
Q

Type I Antimicrobials

A

Concentration Dependent

Fluoroquinolones, Metronidazole, Aminoglycosides

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9
Q

Type II

A

Time Dependent

Sulfonamides, Diaminopyrimidines, B-lactams, Macrolides, Chloramphenicol, Lincosamides

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10
Q

Type III

A

Time dependent w/kinetic PAE

Tetracyclines and Azithromycin

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11
Q

Bactericidals

A

B-lactams, Fluoroquinolones, Metronidazoles, Aminoglycosides, Polymyxin B, Colistin

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12
Q

Narrow Spectrum

A

B-lactams, Aminoglycosides, Polymyxin B, Colistin

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13
Q

Increase pH = Increase Action

A

Sulphonamides, Fluoroquinolones, Macrolides

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14
Q

Decrease pH = Increase Action

A

Aminoglycosides, Rifampin

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pharm 2 - final review (6 decks)

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