Oncology Flashcards
1
Q
List the 3 most common markers for T cells
A
CD 3, 4, 8
2
Q
List the 3 most common markers for B cells
A
CD 79a, 20, 21
3
Q
What is PARR?
A
PCR for antigen receptor rearrangement - clonality assay, detects a set of genes that are unique to the B cell or T cell, not useful for staging, can be used for remission, looking for a monoclonal expansion (who are the cells)
4
Q
In the JVIM 2013 paper comparing IHC, flow, and PARR for the diagnosis of lymphoma, which was found to be the most specific for phenotype?
A
Flow cytometry, if have fresh cells
5
Q
Pros/cons urinary alkalinization with TLS?
A
increases uric acid solubility but decreases CaPh excretion; avoided in human medicine
