Pharm 1 exam 2

Question 1

What are the adverse effects of Levodopa?

Answer 1

N/V, Dyskinesias, dysrhythmia, psychosis, dark sweat and urine, activat malignant melanoma.

Question 2

A/E of the “capones” (entacapone, tolcapone)

Answer 2

Same as Pramiprexole. Flu-like symptoms, impulse control.

Question 3

A/E of Pramipexole:

Answer 3

N/V, dizzy, daytime sleepiness, insomnia, GI, weakness, hallucinations, impulsive behaviors.

Question 4

A/E of Selegiline:

Answer 4

Insomnia O. hyptension, dizzy, GI.

Question 5

A/E of Amantadine:

Answer 5

Dry mouth, urinary retention, blurred vision, anxiety, confusion.

Question 6

What are the A/E of the cholinesterase Inhibitors used in Alzheimers disease?

Answer 6

(Denepizil, Galantamine, Rivastigmine, Memantine)

-N/V/D, Dizzy, bronchioconstriction in COPD and asthma.

Question 7

What are the Immunomodulater drugs used for Multiple Sclerosis?

Answer 7

• Interferon beta 1a
• Interferon beta 1b
• Glateramer Acetate
• Natalieazumab
• Fingolimod

Question 8

What are the A/E of the Immunomodulators?

Answer 8

• Flu like symptoms
• Hepatotoxicity
• Decreased production of all blood cells
• soreness/redness at injection site.
• Depression

Question 9

What is the immunosuppressant used for Multiple Sclerosis?

Answer 9

Mitoxantrone.

Question 10

What are the Adverse effects of Mitoxantrone?

Answer 10

Myelosuppression, cardiotoxicity, TERATOGENIC, GI, can turn skin, sclera, and urine blue.

Question 11

What are the 2 centrally acting muscle relaxants used for spasms?

Answer 11

Diazepam and Lorazepam

Question 12

What are the A/E of Diazepam and Lorazepam?

Answer 12

Dizzy, drowsy, sedation, physical dependence. Make sure they withdraw slowly from it. Avoid alcohol.

Question 13

What are the 2 drugs for spasticity?

Answer 13

Baclofen and Dantrolene

Question 14

What are the A/E of Baclofen?

Answer 14

Drowsy, dizzy, weakness, fatigue, avoid alcohol. Withdraw slowly to prevent seizures.

Question 15

What are the A/E of Dantrolene?

Answer 15

drowsy, hepatotoxicity, weakness, diarrhea.

Question 16

What are the Adrenergic antagonists and what are there adverse effects?

Answer 16

The “osins”

-Orthostatic hyptension, reflex tachycardia, Nasal congestion, Inhibition of ejaculation.

Question 17

What are the Beta blockers? What are the therapeutic uses of the beta blockers?

Answer 17

• The “olols”

- Angina, HTN, dysrhythmia, MI, Heart failure.

Question 18

What are the A/E of the Beta blockers? (“olols”)

Answer 18

Bradycardia, decreased CO, heart failure, AV heart block, rebound cardiac excitation, bronchoconstriction.

Question 19

What class of drugs are used to treat Alzheimer’s disease?

Answer 19

Cholinesterase Inhibitors.

Question 20

What are the Cholinesterase inhibitors used to treat Alzheimer’s and what are their A/E?

Answer 20

• Denepizel, Galantamine, Rivastigmine, Memantine.

- A/E: N/V, dyspepsia (indigestion), diarrhea, bronchoconstriction.