Pharm 1 Exam 3

Question 1

What are the A/E of the Local anesthetics? (“Caines”)

Answer 1

• CNS excitation followed by depression
• Bradycardia, decreased contractions, MI.
• Labor and Delivery: Depressed uterine contractions. Can cross the placenta.
• Methemoglobinemia: (benzocaine)

Question 2

What are the A/E of the general anesthetics?

Answer 2

• N/V
• bradycardia, respiratory and cardiac depression.
• Dysrythmia
• MALIGNANT HYPERTHERMIA
• aspiration of gastric contents
• spontaneous abortions.

Question 3

What are the uses of the Opioids?

Answer 3

• Pain (best for dull pain)
• Cough suppression
• COPD (it eases air hunger)

Question 4

What are the A/E of the Opioids?

Answer 4

• Respiratory depression
• Constipation
• Orthostatic Hyptension
• Urinary retention
• Cough suppression
• N/V
• Increased ICP
• Miosis
• TERATOGENIC

Question 5

What is the drug of choice for Migraines?

Answer 5

Ergotamine

Question 6

What drugs should you never mix with the “triptans?”

Answer 6

Ergo Alkyloids

Question 7

Are headache meds ok to take while pregnant?

Answer 7

NO. Most of them are teratogenic.

Question 8

If a diabetic gets pregnant, what do they need to make sure they do?

Answer 8

Take Insulin and stay away from oral meds for diabetes!

Question 9

How does alcohol effect insulin?

Answer 9

It lowers the amount of insulin needed.

Question 10

What are the drugs with each and what is the risk of too much…

1) 2nd generation sulfonylurease
2) Biguanides
3) Alpha glucosidase inhibitors
4) Meglinitides
5) Thizaolidinediones
6) Gliptins

Answer 10

1) Glyburide, glimepiride, glipizide. Hypoglycemia.
2) Metformin. Lactic Acidosis
3) Acarbose, miglitol. Gas, diarrhea, stomach pain.
4) Repaglinide, nateglinide. Hypoglycemia.
5) Pioglitazone. hypoglycemia, High LDL’s.
6) “gliptins.” Pancreatitis and anaphylaxis

Question 11

What meds are used to treat hypothyroid? What are their A/E?

Answer 11

• Levothyroxine
• Liothyronine
• Liotrix
• Thyroid
• Overmedication causes symptoms of hyperthyroidism.

Question 12

What meds are used to treat Hyperthyroidism (graves disease)?

Answer 12

• Propylthiouracil (PTU), Methimazole
• Radioactive Iodine
• Lugol’s Solution, Sodium Iodide, Potassium Iodide

Question 13

What are the A/E of PTU? Can it be taken during pregnancy?

Answer 13

• hypothyroidism symptoms, agranulocytosis, hepatitis

- It is safe through the first trimester ONLY.

Question 14

What are the A/E of Radioactive Iodine?

Answer 14

Radiation sickness, hypothyroidism, myeosupression

Question 15

What are the A/E of Lugol’s Solution?

Answer 15

Iodism (sore teeth, gums, metallic taste, rash, headache)

Question 16

What drugs are used to treat Growth hormone deficiency?

Answer 16

Somatropin and somatrem

Question 17

What are the A/E of Somatropin?

Answer 17

Hyperglycemia, hypercalcuria, renal calculi

Question 18

What are the contraindications of Somatropin?

Answer 18

Obesity and sleep apnea.

Question 19

What is used to treat Diabetes insipidus?

Answer 19

Vasopressin and desmopressin

Question 20

What is Estrogen Therapy used for?

Answer 20

• Menopausal hormone therapy
• Female hypogonadism
• Acne

Question 21

What are the A/E of Estrogen therapy?

Answer 21

Endometrial hyperplasia, BREAST CANCER, ovarian cancer and uterine cancer.

Question 22

What is progestin used for?

Answer 22

• It prepared the uterus for implantation and maintains it through pregnancy.
• Suppress uterine contractions in preterm birth.

Question 23

What are the A/E of progestins?

Answer 23

Cardiovascular events, endometrial cancer, breast cancer, ovarian cancer, lung cancer, gallbladder disease.

Question 24

Who is birth control Absolutely contraindicated for?

Answer 24

Patients with…Thrombophlebitis, abnormal liver function, breast cancer, vaginal bleeding, pregnant and smokers over 35.