Skin

Question 1

What does the word Lentigo mean?

Answer 1

Flat - spreading out

Question 2

What is meant by the word nevus?

Answer 2

Melanocytic nevi are nests of multi-layered melanocytes aka moles

Question 3

What characteristics indicate that a nevus may be dysplastic?

Answer 3

Nevi are larger and irregular and may have pigment variation

Under the microscope the nevus exhibits cytological and architectural atypic

Question 4

What can Acanthosis Nigricans be an indication of?

Answer 4

Obesity and Hypersinsulinism

Question 5

What is the Sign of Leser-Trelat?

Answer 5

Sudden development of multiple lesions may accompany an underlying malignancy

Question 6

What are the tests called you can use on physical exam to evaluate Psoriasis and Pemphigus?

Answer 6

Auspitz sign - Psoriasis

Nikolski’s sign - Pemphigus

Question 7

What is the relationship between topical steroid and Tenia infections of the skin?

Answer 7

Topical steroid are NOT used in conjunction with antifungals.
The topical steroids decrease the efficacy of the anti fungal because corticosteroids suppress the immune system

Question 8

What is the difference between Erythema Nodosum and Erythema Multiforme?

Answer 8

Erythema Multiforme: a hypersensitivity skin reaction to infections of drugs like SULFONIDES, think TARGET lesions, STEVEN-JOHSNSON

Erythema Nodosom: associated with granulomatous disease and STREP infection. Painful nodules on SHINS. Resoloves on its own in 3-4 weeks. Common in young people.

Question 9

What layers are involved with the following: BCC, SCC, Melanoma

Answer 9

Squamous Cell Carcinoma: arise in Keratinocytes (upper layer)
Basal Cell Carcinoma: arise in basal layer of keritinocytes
Melanoma: arises in melanocytes at the dermal epidermal junction (deepest)