Genes of embryogenesis Flashcards

1
Q

Shh

A

Limb base in the zone of polarizing activity
Pattern along AP axis
CNS development
(mutation=holoprosencephaly)

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2
Q

Wnt7

A

Apical ectodermal ridge
(distal end of each developing lib)
Pattern along DV axis (vs. SHH)

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3
Q

FGF

A

Apical ectodermal ridge
Stimulates mitosis of underlying mesoderm.
Lengthening of limbs

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4
Q

Hox

A

Segmental organization of embryos in craniocaudal direction.

Mutation = appendages in wrong locations

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