Embryology Basic Body Plan Flashcards

0
Q

four major steps in week one of development

A

fertilization
cleavage
blastocyst formation
implantation

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1
Q

fertilization occurs in

A

the ampulla of the uterine tube

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2
Q

resultant cells of cleavage are called

A

blastomeres

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3
Q

blastomeres are totipotent up to

A

the 4-8 cell stage

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4
Q

16-32 cell stage of cleavage is called

A

morula

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5
Q

2 processes that turn a morula into a blastocyst

A

compaction and cavitation

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6
Q

cleavage occurs between (time)

A

1-4 days

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7
Q

inner cell mass of blastocyst: name, and becomes

A

embryoblast, becomes embryo

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8
Q

outer cell mass of blastocyst, name and becomes

A

trophoblast, becomes fetal portion of placenta

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9
Q

cell type in embryoblast

A

pluripotent stem cells

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10
Q

morula compacts and cavitates to become _____ at _____ (time)

A

blastocyst, 4.5-5 days

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11
Q

blastocyst implants in uterine wall by (time)

A

6-7 days

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12
Q

ruptured follicle becomes

A

corpus luteum

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13
Q

corpus luteum produces

A

progesterone

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14
Q

progesterone does what to the uterus

A

enter secretory phase

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15
Q

which cells of the blastocyst invade the uterine epithelium

A

trophoblasts

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16
Q

what hormone is produced by trophoblasts as they invade uterine epithelium?

A

human Chorionic Gonadotropin (hCG)

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17
Q

Trophoblast during week two

A

differentiates into syncytiotrophoblast (outer layer) and cytotrophoblast (inner layer)

18
Q

embryoblast during week two

A

differentiates into epiblast and hypoblast

19
Q

epiblast during week two

A

secretes fluid to form the amniotic cavity

20
Q

hypoblast in week 2

A

line blastocyst cavity, form primitive yolk sac

21
Q

trophoblast lacunae do what

A

connect to sinusoids in endometrial stroma

22
Q

embryo is embedded in endometrial stroma by (time)

A

12 days

23
Q

new cavity formed by hypoblast in week two

A

chorionic cavity

24
Q

lining of chorionic cavity

A

extraembryonic mesoserm

25
Q

dizygotic twins constitute ____% of twinning cases

A

70

26
Q

monozygotic twins constitute ____% of twinning cases

A

30

27
Q

monozygotic twin spits at early blastocyst

A

separate amnion, common chorion and placenta

28
Q

monozygotic twins split at late blastocyst

A

common chorion, amnion and placenta

29
Q

pregnancy without an embryo

A

hyatidiform mole

30
Q

lab and clinical signs of hyatidiform mole

A

high hCG, vaginal bleeding, large uterus

31
Q

β€œIt is not birth, marriage, or death, but ________, which is truly the most important time in your life.” Lewis Wolpert

A

gastrulation

32
Q

gastrulation occurs in (time)

A

week 3

33
Q

gastrulation establishes _______ and defines ________

A

3 germ layers of the embryo

body axes

34
Q

during gastrulation, epiblast cells

A

invaginate at the caudal midline (primitive streak) and migrate to replace hypoblast

35
Q

replacement of hypoblast cells with epiblast cells froms

A

endoderm

36
Q

epiblast cells that migrate between hypoblast and epiblast form

A

the mesoderm

37
Q

after gastrulation, the epiblast is called

A

the ectoderm

38
Q

ectoderm becomes

A

nervous system, epidermis, sensory epithelium of nose, ear, and eye

39
Q

mesoderm becomes

A

muscle, cartilage, bone, connective tissue, parts of kidney and gonads

40
Q

endoderm becomes

A

epithelium of gut, epithelium of respiratory system

41
Q

caudal dysgenisis aka

A

sirenomelia

42
Q

caudal dysgenesis caused by

A

abnormal gastrulation, migration is disturbed, insufficient caudal mesoderm

43
Q

period of maximal sensitivity to abnormal development

A

3-8 weeks