2.6 Structure of DNA and RNA Flashcards

1
Q

What are the 3 components of a nucleotide?

A

5 carbon pentose sugar
Phosphate group
Nitrogenous base

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2
Q

Which carbons are bound in a nucleotide?

A

Nitrogenous base attaches to the 1’

Phosphate base attaches to the 5’

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3
Q

What does DNA stands for?

A

Deoxyribonucleic acid

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4
Q

What does RNA stand for?

A

Ribonucleic acid

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5
Q

What is the difference in the pentose sugar in RNA and DNA?

A

RNA has ribose

DNA has deoxyribose

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6
Q

What are the bases in RNA?

A

A, C, G and U

Adenine, Cytosine, Guanine and Uracil

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7
Q

What are the bases in DNA?

A

A, C, G and T

Adenine, Cytosine, Guanine and Thymine

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8
Q

How do different nucleotides bond?

A
  • Phosphate grp of one nucleotide attaches the the sugar of another (3’ - OH)
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9
Q

What kind of bond holds nucleotides together?

A

Phosphodiester

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10
Q

What is the by-product of Nucleic acids bonding?

A

Water

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11
Q

How do adenine and thymine bond?

A

2 hydrogen bonds

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12
Q

How do guanine and cytosine bond?

A

3 hydrogen bonds

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13
Q

Why do we say DNA is antiparrallel?

A

Because the two strands run in opposite directions to one another

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14
Q

What is the arrangement of DNA?

A

A double helix with about 10-15 bases per twist

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15
Q

Who proposed the current DNA structure?

A

James Watson and Francis Crick

1953

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16
Q

Which bases are purines?

A

Adenine and Guanine

17
Q

Which bases are pyrimidines?

A

Cytosine and Thymine

18
Q

Who organised DNA into a helical structure?

A

Rosalind Franklin

19
Q

How did R. Franklin confirm the DNA arrangement?

A

Using x-ray crystallography