Endocrine Disorders

Question 1

Deficiency of one or more anterior pituitary hormone

Answer 1

hypopituitarisim

Question 2

Most life threatening pituitary deficiency

Answer 2

Deficient ACTH and TSH

Question 3

Leads to short stature and other manifestations of growth retardation

Answer 3

GH deficiency in children

Question 4

Increases rate of bone destructive activity

Answer 4

GH deficiency in adults

Question 5

Most effective route of androgen replacement

Answer 5

IM route for androgens

Question 6

Presence of male secondary sex characteristics

Answer 6

virilization

Question 7

Oversecretion of homrones that occur with pituitary tumors or tissue hyperplasia

Answer 7

Hyperpituitarism

Question 8

Pituitary hormone that blocks action of insulin

Answer 8

GH effects on insulin

Question 9

high blood glucose levels suppress this pituitary hormone

Answer 9

glucose effects on GH

Question 10

This drug therapy for management of hyperpituitarism should be with meals

Answer 10

bromocriptine (Parlodel)

Question 11

Most common treatment of hyperpituitarism

Answer 11

transsphenoidal hypophysectomy

Question 12

Postop instructions for transphenoidal hypophysectomy

Answer 12

Don’t brush teeth, cough, sneeze, blow the nose, or bend forward

Question 13

Water metabolism problem caused by ADH deficiency

Answer 13

Diabetes Insipidus

Question 14

Reduced secretion of this hormone causes potassium excretion to decrease and sodium/water to be retained

Answer 14

Decreased aldosterone

Question 15

Life-threatening event in which the need for cortisol and aldosterone is greater than the available supply

Answer 15

Addisonian Crisis (acute adrenal insufficiency)

Question 16

Sudden cessation of long-term glucocorticoid therapy can lead to this condition.

Answer 16

Common cause of secondary Addison’s disease

Question 17

3 main interventions for Addisonian crisis

Answer 17

Hormone replacement
Hyperkalemia management
Hypoglycemia management

Question 18

Low: serum cortisol, low FBG, low Na,
High: K, Eosinophil, ACTH

Answer 18

Common lab changes for adrenal insufficiency

Question 19

The most definitive test for adrenal insufficiency

Answer 19

ACTH Stimulation test

Question 20

The cortisol response in primary adrenal insufficiency after ACTH stim test

Answer 20

Absent or decreased cortisol during ACTH stim test indicates this condition

Question 21

The cortisol response in secondary adrenal insufficiency after ACTH stim test

Answer 21

Increased cortisol during ACTH stim test indicates this condition

Question 22

Hypersecretion by the adrenal cortex results in this

Answer 22

Cushing’s disease (endogenous) or Cushings syndrome (exogenous)

Question 23

Hyperstimulation of the adrenal medulla is caused by this problem

Answer 23

tumor (pheochromocytoma)

Question 24

Truncal obesity, moon face, buffalo hump, thinner arms and legs, abdominal striae are typical of this condition

Answer 24

Typical apperance of a patient with Cushing’s disease/syndrome

Question 25

Excess in this class of hormones affects metabolism of all body systems

Answer 25

Excess glucocorticoids

Question 26

High levels of this class of hormones can kill lymphocytes and shrink organs containing lymphocytes, inhibit macrophage activity, and reduce antibody production.

Answer 26

Excess corticosteroids effect on immune system

Question 27

Treatment of Asthma, Autoimmune disorders, Organ transplant, Cancer chemotherapy, Allergic responses, and Chronic fibrosis are treated with these hormones

Answer 27

Common uses of ACTH or glucocorticoid medications

Question 28

Increases in this hormone can cause acne and hirsutism

Answer 28

Increased androgen production

Question 29

These hormones increase metabolism in all body organs

Answer 29

Thyroid hormones

Question 30

Net loss of body protein that occurs when protein degradation occurs faster than synthesis

Answer 30

negative nitrogen balance

Question 31

Autoimmune disorder in which antibodies are made and attach to the TSH receptors which causes a goiter and over produces thyroid hormones.

Answer 31

Grave’s disease