gluconeogenesis Flashcards
1
Q
first irreversible step of gluconeogenesis
A
pyruvate to OAA by pyruvate carboxylase
2
Q
pyruvate carboxylase is found where?
A
mitochondria
3
Q
where is PEP carboxykinase found
A
mitochondria and cytosol
4
Q
OAA is converted to PEP by
A
PEP carboxykinase ( uses GTP)
5
Q
coenzyme of pyruvate carboxylase
A
biotin
6
Q
pyruvate carboxylase is allosterically activated by
A
acetyl coA
7
Q
how does OAA cross the mitochondrial membrane
A
its reduced to malate by NADH
8
Q
free fatty acids that are released by adipocytes during fasting are bound to what in the blood stream
A
albumin
9
Q
acetyl coA from b-oxidation of fatty acids is used to activate
A
pyruvate carboxylase
