ROS Flashcards
1
Q
where is superoxide formed
A
electron transport chain by coQ or by cytochrome p450
2
Q
haber-weiss reaction
A
superoxide + hydrogen peroxide = hydroxyl radical
3
Q
fenton reaction
A
superoxide + Fe2+ = OH-
4
Q
eliminates 2 superoxides to form 1 hydrogen peroxide
A
superoxide dismutase
5
Q
eliminates 2 hydrogen peroxides to form water and O2
A
catalase (found in peroxisomes)
6
Q
can eliminate 1 hydrogen peroxide at a time but can also eliminate organic peroxides
A
gluthatione peroxidase (selenium)
7
Q
NADPH oxidase is found where
A
neutrophil cell membranes (makes superoxide for defense)
8
Q
hereditary deficiency in NADPH oxidase
A
chronic granulomatus disease (bridges-good syndrome)
9
Q
makes hypochlorus acid for defense against fungi
A
myeloperoxidase
