Midterm-Slide Set 4 Flashcards
Define afferent
sends info to the CNS
Define efferent
sends info from the CNS
Where does the SNS send its signals?
skeletal muscles
What are the effectors of the ANS?
glands and smooth and cardiac muscles
What is the sympathetic division of the ANS?
prepares the body to deal with immediate threats to the internal environment
What is the parasympathetic division of the ANS?
coordinates the body’s normal resting activities
Explain how the parasympathetic system works on the stomach
the distension (stretching) of the stomach in the presence of food causes the parasympathetic system to mucosa to release Gastrin, which increases the secretion of gastric juices
Explain how the sympathetic system works on the heart
stimulates SA node by releasing norepinephrine, which acts by accelerating inactivation of K channels. Cell becomes less negative, swifter drift to AP, heart beats more to pump more blood, has a vasoconstriction effect on the blood vessels
What is the cytoskeleton of neurons made of?
microtubules and microfilaments and neurofibrils (bundles of neurofilaments= intermediate filaments)
What are the four types of glial cells?
oligodendrocytes, microglia, astrocytes, and ependymal cells
Where do the cell extensions of astrocytes connect to?
neurons and capillaries
what is the function of astrocytes?
transfer nutrients from the blood to the neurons and form tight sheaths around brain capillaries (BBB)
What is the blood-brain barrier (BBB)?
the specialized system of capillary endothelial cells that protects the brain from harmful substances in the blood stream while also allowing for supplying the brain with the required nutrients for proper function
How does the BBB protect the brain?
BBB strictly limits transport into the brain through both physical (tight junctions) and metabolic (enzymes) barriers
How do astrocytes contribute to the BBB?
webs of astrocytes form tight sheets around the brain’s capillaries creates a double barrier with the capillary endothelial cells
What are liposomes and how do they work with the BBB?
vesicles with a phospholipid bilayer membrane. liposomes can fuse with other bilayers to deliver its contents
What are microglia cells?
the macrophages of the brain, usually stationary except in inflamed brain tissue
What are ependymal cells?
some produce fluids, others aid in circulation of fluids. polarised nucleus bc there are cilia on the other end. they are the stem cells of the brain
What are oligodendrocytes?
hold nerve fibers together & PRODUCE MYELIN SHEATH in CNS. small than astrocytes with fewer processes
What is multiple sclerosis?
MS is the malfunction of oligodendrocytes (loss of myelin sheath). plaque-like lesions detected by MRI
What are Schwann cells?
functionally similar to oligodendrocytes but found only in the PNS. support nerve fibers and sometimes form myelin sheath