Pulmonary Embolism, D Kinder, DSA Flashcards

1
Q

definition PE

A

obstruction of pulmonary a through blood stream

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2
Q

soureces of PEs

A

DVT, fat, amniotic fluid, air, tumor cells, talc in venous drug users and medical devices

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3
Q

Risk factors venous thromboembolism

A

advanced age, history previous VTE, obesity, active cancer

limit activity

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4
Q

What are the triggering factors for VTE

A

surgery, pregnancy immobiliazation or estrogen therapy

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5
Q

What is virchows triad

A

vascular damage, stasis and hypercoagulability

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6
Q

what are genetic hypercoaguable states

A

factor V ledien, prothrombin 20210 gene mutation
antithrombin deficiency
protein C deficiency
protein S deficiency

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7
Q

most PE come from what

A

DVT

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8
Q

what is risk factor for DVT from UE

A

indwelling catheter

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9
Q

signs and Sx PE

A

dyspnea, tachypnea, hypoxemia, pleuritic chest pina, cough, hemoptysis, leg pain, swelling, palpiations, syncope, split second heart sounds with loud pulmonic componenent

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10
Q

Ddx PE

A

pneumonia, COPD excacerbation, asthma, pleurisy, CHF, acute coronary syndrome, pericarditis and MSK disorders

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11
Q

What are the tests for PE

A
D-dimer
CT pulm angiography
VQ scan
pulm angiography
venous compression US of LE
EKG
echo
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12
Q

what is D-dimer test

A

negative predictive value in patients with low-moderate pre-test probability PE

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13
Q

what is the gold standard now for PE

A

CT pulm angiography

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14
Q

what are the parts of VQ scan

A

inhale xenon or tecnetium

IV injection of technetium labeled macroaggregates of albumin

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15
Q

what is preferred test for PE in pregnant women

A

VQ scan

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16
Q

what is the sensitivity and specificity of venous compression US LE DVT

A

95%

17
Q

What is the EKG pattern of PE

A

S1 Q3 T3
RBBB
limited sensitivity

18
Q

what does echo show in PE

A

right ventricular dysfunction, dilation or hypokinesis

19
Q

Tx PE

A

O2 and fluids
inotropic agents if right ventricular fialure
systemic reperfusion therapy with fibrinolytics if severe
! anticoagulants

20
Q

What are the anticoagulatns used for PE Tx

A
heparin
LMWH
warfarin
rivaoxaban
caval filters
21
Q

what type drug is rivaroxaban

A

factor Xa inhibitor

22
Q

what factor does warfarin antagonize

A

Vitamin K