Pharmacology Addictive Substances (6.3) Flashcards
The following are symptoms of:
anxiolysis, disinhibition, slurred speech, ataxia, stupor, respiratory suppression, coma, death
Alcohol or benzo/ barbituate intoxication
How do you treat alcohol intoxication?
Support, restraint, protect airway, ventilate
The following are symptoms of:
agitation, insomnia, tremor, GI upset, increase pulse, seizures, hallucinations, delerium, death
Alcohol or Benzo/ barbituate withdrawal
When do symptoms of alcohol withdrawal begin?
8 hours after last drink
When do alcohol withdrawal symptoms peak?
24 hours
How do you treat benzo/ barbiturate intoxication?
Support, restraint, protect airway, ventilate
Benzo can be reversed with flumazenil
How do you treat withdrawal from benzo/ barbiturates?
Treat with benzo replacement until vital signs and withdrawal symptoms normalize
How do stimulants work?
Block dopamine reuptake
The following are symptoms of:
elevated mood and esteem, irritability, insomna, appetite loss, dilated pupils, racing heart, increase BP, hyperreflexia, psychosis, cardiac arrest, seizure
intoxication of stimulants
The following are symptoms of:
fatigue, anhedonia, depression, increased sleep, late onset insomnia, increased appetite
Withdrawal from stimulants
How do you treat stimulant intoxication and withdrawal?
Support, symptomatically
What receptors do opiates affect?
Mu–> reduces pain, increases positive emotion
Kappa/ Delta–> minld analgesia
How do Mu/ Kappa/ Delta receptors work?
G protein lined and cause hyperpolarization via cAMP reduction and increased K influx/ decreased Ca efflux
The following are symptoms of:
elevated mood, pupil constriction, respiratory suppression, gag reflex lost, low HR, constipation, low BP
opiate intoxication
The following are symptoms of:
restless, watery eyes, yawning, dilated pupils, good flesh, runny nose, increased HR, increased PB, GI distress and cramps, muscle cramps
opiate withdrawal
