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Biochem Post Midterm > Lipoproteins > Flashcards

Lipoproteins Flashcards

1
Q

lipoprotein with the most protein content

A

HDL

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2
Q

lipoprotein with the most TAG content

A

chylomicrons

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3
Q

integral protein found on chylomicrons

A

apo b-48

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4
Q

chylomicrons bind to LDL receptors in the liver using which peripheral protein

A

apo E

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5
Q

chylomicrons bind to lipoprotein lipase in adipose tissue using which peripheral protein

A

apo C

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6
Q

integral protein found on VLDL

A

apo b-100

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7
Q

lipoprotein with the most cholesterol

A

LDL

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8
Q

why does LDL stay in the body longer

A

it is lacking apo E that is recognized by the liver. it only has apo b-100 that is recognized by the liver but has a much lower affinity that apo E

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9
Q

integral protein found on HDL

A

apo A

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10
Q

function of LCAT

A

binds to HDL and esterifies cholesterol in cell membranes to make them more hydrophobic, so that they can be collected by HDL

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11
Q

Small white appearance on the retina

A

lipimea retinalis

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12
Q

Foam cells that deposit subcutaneously and on tendons

A

xanthomas

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13
Q

Cholesterol deposits underneath the eyelids

A

xanthelasmas

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14
Q

Delivers cholesterol to the tissues

A

LDL

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15
Q

LDLs deliver cholesterol to the tissues via

A

endocytosis

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16
Q

Increased Chylomicrons,
defective apo C-II or decreased LPL, creamy layer on top of serum, pancreatitis, lipemia retinalis, xanthomas on trunk and extremities

A

hyperlipidemia type I

17
Q

Increased IDL
Lack of Apo E
palmar xanthomas

A

hyperlipidemia type III

18
Q

Increased VLDL
pancreatitis
defective LPL

A

hyperlipidemia type IV

19
Q

Increased VLDL, Increased LDL

defective LDL receptor

A

hyperlipidemia type II-b

20
Q

Increased LDL
defective LDL receptor
tendon xanthomas

A

hyperlipidemia type II-a

21
Q

genetic inheritance of hyperlipidemia type II-b

A

autosomal dominant

22
Q

Increased VLDL, Increased Chylomicrons
Decreased LPL
creamy layer on top of serum
pancreatitis

A

hyperlipidemia type V

23
Q

treatment for hyperlipidemia type I

A

diet and omega 3

24
Q

treatment for hyperlipidemia type II-type V

A

statins, niacin, fibrates

25
Q

Lipoprotein that carries vitamins ADEK

A

Chylomicrons

26
Q

Function of B-48

A

Allows chylomicrons to enter lymph

27
Q

Apoprotein that allows VLDL to leave to liver

A

Apo B100

28
Q

Low HDL
Defective abc transporter for cholesterol
Orange tonsils

A

Tangiers

Biochem Post Midterm (24 decks)

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