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Biology4351 > Anxiolytics, Hypnotics, Antidepressants, Neuroleptics and Drugs of Abuse > Flashcards

Anxiolytics, Hypnotics, Antidepressants, Neuroleptics and Drugs of Abuse Flashcards

1
Q

SSRI’s are a class of _

A

Antidepressants

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2
Q

True/False: Caffeine is a bronchodilator

A

TRUE- Caffeine is a bronchodilator

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3
Q

Ethanol is a _, _, and _, depressant?

A

Myocardial
Respiratory
CNS

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4
Q

True/False: Methamphetamine increases DA release

A

TRUE

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5
Q

True/False: Neuroleptics can be used as antiemetic agents

A

TRUE

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6
Q

How do SSRI’s work?

A

SSRI’s block the reuptake of 5-HT, making more 5-HT available

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7
Q

Fluoxetine (Prozac) is in a class of _ called _

A

Antidepressants, SSRI’s

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8
Q

The Biogenic Amine Theory explains depression with _

A

a deficiency in biogenic amines NE or 5-HT

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9
Q

Side effects of SSRI’s include…

A

reduced libido, affected appetite, and possibly seratonin syndrome.

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10
Q

Amitriptyline (Elavil) is in a class of _ called _

A

Antidepressants, TCA’s

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11
Q

How do TCA’s work?

A

TCA’s block the reuptake of 5-HT and NE, making more 5-HT and NE available

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12
Q

Side effects of TCA’s include…

A

anticholinergic side effects, drowsiness, hypotension, and a1 blockade.

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13
Q

TCA’s are a class of _

A

Antidepressant

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14
Q

MAOI’s are a class of _

A

Antidepressant

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15
Q

Low dose manifestations of nicotine does what to the autonomic nervous system?

A

Stimulates autonomic ganglia, increasing sympathetic and parasympathetic divisions

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16
Q

High dose manifestations of nicotine does what to the autonomic nervous system?

A

Causes ganglionic blockade, shutting down autonomic nervous system

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17
Q

How does ethanol exacerbate ulcer problems?

A

Increases HCl secretion

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18
Q

True/False: Ethanol is a vasodilator

A

TRUE- Ethanol is a cutaneous vasodilator

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19
Q

How does cocaine cause euphoria?

A

Blocks NE, DA, 5-HT reuptake

20
Q

How can cocaine cause psychosis?

A

Cocaine reduces reuptake of DA, leading to excessive DA, which is associated with psychosis.

21
Q

True/False: Cocaine is a vasoconstrictor

A

TRUE- Cocaine is a vasoconstrictor

22
Q

Excessive DA is associated with _

A

Psychosis

23
Q

Two DA pathways of the CNS:

A

Nigrostriatal + Mesolimbic Pathway

24
Q

The nigrostriatal pathway is associated with

A

Voluntary motor control

25
Q

The mesolimbic pathway is associated with

A

Regulation of behavior and emotion

26
Q

DA deficiency is associated with _

A

Parkinson’s Disease

27
Q

Rationale behind neuroleptics:

A

reduce DA levels

are DA antagonists

28
Q

Rationale behind antidepressants:

A

increase NE and/or 5-HT levels

29
Q

Two classes of neuroleptics:

A

Typical and Atypical neuroleptics

30
Q

Typical neuroleptics target…

A

the nigrostriatal and mesolimbic pathway

31
Q

Atypical neuroleptics target…

A

the mesolimbic pathway

32
Q

Side effects of typical neuroleptics include:

A

Extrapyramidal Symptoms: involuntary tremors, movement disorders

33
Q

Haloperidol (Haldol) is in a class of _ called _

A

Antipsychotics, TYPICAL neuroleptics

34
Q

Risperidone (Risperdal) is in a class of _ called _

A

Antipsychotics, ATYPICAL neuroleptics

35
Q

Side effects of typical neuroleptics come from unintentional targeting of _ pathway

A

nigrostriatal

36
Q

Diazepam (Valium) is classified as an _ and _

A

Anxiolytic, Hypnotic

37
Q

Diazepam inhibits CNS activity by _

A

enhancing GABA effect

38
Q

Benzodiazepines are used short-term because…

A

the abuse potential is high

39
Q

Benzodiazepines are used as _, _, and _, but can also function as an _ .

A

anxiolytic; hypnotic; muscle relaxer; anti-seizure agent

40
Q

Buspirone (Buspar) is a _ that works as a __ agonist.

A

anxiolytic; 5-HT receptor

41
Q

Diazepam (Valium) is in a class of _ & _ called _

A

anxiolytics & hypnotics; benzodiazepines

42
Q

Diazepam (Valium) and Buspirone (Buspar) are both _.

A

anxiolytics

43
Q

Diazepam (Valium) is a _ whereas Buspirone (Buspar) is not.

A

hypnotic

44
Q

Fluoxetine (Prozac) and Amitryptyline (Elavil) are both _.

A

antidepressants

45
Q

Haloperidol (Haldol) and Risperidone (Risperdal) are both _.

A

antipsychotics

46
Q

Haloperidol (Haldol) is associated with _ whereas Risperidone (Risperdal) is not.

A

Extrapyramidal symptoms

Biology4351 (16 decks)

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