2nd Credit Test - Deck 9 Flashcards
(15 cards)
In inflammation, IL-1 is responsible for:
Formation of acute-phase proteins.
Pain and fatigue.
Sickness behavior (lethargy, loss of appetite).
Acute vascular reaction in inflammation is manifested by:
Increased permeability of blood vessels and the formation of oedema.
The role of the ….. is to trap antigens from the blood.
Spleen
The role of the ….. is to ensure the maturation of T lymphocytes.
Thymus
The role of the ….. is to ensure the maturation of B lymphocytes.
Bone marrow
The role of the ….. is to trap antigens from the tissue.
Lymph node
The slowing of movement and rolling of leukocytes along the vascular endothelium induces the presence of pro-ininflammatory cytokines and chemotactic molecules that activate the expression of ..… on the surface of circulating leukocytes and activated endothelium.
Selectins
In a strong binding of leukocytes to the activated endothelium induces the presence of pro-inflammatory cytokines and chemotactic molecules that activate the expression of ….. on the surface of circulating leukocytes.
Integrins
The extravasation of leukocyes through the intact capillary wall by diapedesis is mediated by interactions between ….. on migrating leukoytes and endothelial cells.
PECAM
NK cells produce ….. responsible for the formation of holes in the cell membrane of the target cell.
Perforins
The ….. complement pathway is activated by the binding of ….. complement component to ….. antibody in antigen-antibody complexes.
Classical
C1q
IgM or IgG
Complement plays an important role in ….. immunity.
Innate/Humoral
Cells that have MHC Class 1 are ….. , which present ….. antigen to …..
Nucleated cells
Endogenous
Tc cells
Cytokines have an ….. effect when they act on cells that are adjacent to the cell that produces them.
Paracrine
Cytokines have an ….. effect when they act on the cell that produces them.
Autocrine
