3 Flashcards
(7 cards)
1
Q
what is ethnopharmacy
A
the study of substances used medicinally, especially folk remedies, by different ethnic or cultural groups
2
Q
how are plant extracts made, what do they contain and how are they turned into medicines
A
- obtained when soaking plant often when dried in a solvent
- contain highly complex mixtures containing thousands of compounds
- to turn it into a medicine we have identify the active compound
3
Q
how are therapeutic compounds isolated in extracts
A
- extensive regime of extraction and separation to identify the compound
- the different solvents are used to make fractions which even then contain a mixture of compounds
- it could be multiple compounds in in combination that give the effect
4
Q
2 way observations of compounds are made
A
- side effects in clinical trials can give compounds a new use
- and retrospectively looking at or repurposing existing drugs
5
Q
why cant rational design be used
A
- a powerful strategy but with certain prerequisites
- it is not always possible to use this route
- requires structural date which is hard to obtain
6
Q
what is high throughput screening, what is it best sued for, what is a limitation, and a pro
A
- robots used to do screen more compounds faster
- good for a starting point but wont give you your final compound
- limited as the compound libraries of compounds is limited
- make multiple variants of a type of compound rapidly
7
Q
what is rational drug design
A
the inventive process of finding new medications based on the knowledge of a biological targe
