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3 Flashcards

(7 cards)

1
Q

what is ethnopharmacy

A

the study of substances used medicinally, especially folk remedies, by different ethnic or cultural groups

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2
Q

how are plant extracts made, what do they contain and how are they turned into medicines

A
  • obtained when soaking plant often when dried in a solvent
  • contain highly complex mixtures containing thousands of compounds
  • to turn it into a medicine we have identify the active compound
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3
Q

how are therapeutic compounds isolated in extracts

A
  • extensive regime of extraction and separation to identify the compound
  • the different solvents are used to make fractions which even then contain a mixture of compounds
  • it could be multiple compounds in in combination that give the effect
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4
Q

2 way observations of compounds are made

A
  • side effects in clinical trials can give compounds a new use
  • and retrospectively looking at or repurposing existing drugs
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5
Q

why cant rational design be used

A
  • a powerful strategy but with certain prerequisites
  • it is not always possible to use this route
  • requires structural date which is hard to obtain
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6
Q

what is high throughput screening, what is it best sued for, what is a limitation, and a pro

A
  • robots used to do screen more compounds faster
  • good for a starting point but wont give you your final compound
  • limited as the compound libraries of compounds is limited
  • make multiple variants of a type of compound rapidly
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7
Q

what is rational drug design

A

the inventive process of finding new medications based on the knowledge of a biological targe

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