3. lab techniques

Question 1

errors that occur with ligands

Answer 1

• not enough
• too much
• doesn’t degrade/reuptake right
• pathogenic (eg. virus)

Question 2

receptor errors

Answer 2

• too many expressed
• too few expressed
• stop responding to correct ligand
• respond to the wrong ligand

Question 3

intracellular pathway errors

Answer 3

• proteins don’t activate
• proteins don’t enter nucleus
• no transcription/translation
• wrong transcription/translation

Question 4

cell signalling disruption and disease

Answer 4

• metabolic disorders
• cancer
• neurodegenerative diseases

Question 5

type I diabetes

Answer 5

• destroyed/impaired beta cells of pancreas
• no insulin produced
• increased blood sugar
• damages tissues and organs

Question 6

type II

Answer 6

• receptors become insensitive to insulin
• increased blood sugar
• damages tissues and organs