M2 L10 Flashcards
(12 cards)
what are 3 types of muscle
smooth, cardiac, skeletal
what is the order of muscle organisation
myofibril -> fibre -> fascicle
muscle nuclei
- multiple from fused cells
- on the periphery of the cell
contractile units of muscle
sarcomere
dark band in light region
light band in dark region
Z disc
M line
ratio of actin to myosin in sarcomeres
2 actin filament: 1 myosin filament
actin
- globular actin each have an active site
- linear actin or fibrous
tropomyosin
thread like along actin surface
- each covers 7 actin active sites
troponin
complex of 3 globular proteins
- I affinity for actin
- T affinity for tropomyosin
- C affinity for calcium
other proteins
a - actinin
- primary Z line comp
titin
- core of thick filament that recoils
- binds myosin to Z disc
nebulin
- act as actin length determiner
thin myofilaments
- actin
- troponin
- tropomyosin
thick myofilament
myosin