chapter 3: lymph nodes Flashcards
two major functions of lymph nodes
- filtration of lymph (via phagocytosis)
- humoral & cell mediated immunities
part of lymph node structure with dense irregular CT of moderate thickness containing trabeculae (septa)
capsule
____ lymphatics of the lymph node are incoming vessels while ____ lymphatics are outgoing. both contain valves
afferent
efferent
recessed area of lymph node where efferent lymph where blood will enter/exit
hilum
subcapsular sinus AKA
-first sinus to receive afferent (“dirty”) lymph
marginal sinus
in the lymph node, the ____ sinus passes through the cortex region, the ____ sinus passes thru the deep cortex/paracortex, and the ___ sinus passes through the medulla region
cortical
deep cortical
medullary
cells w/i all regions and sinuses of the lymph node are supported by a system of ___ ___ which are produced by reticular cells
reticular fibers
the ___ of a lymph node contains macrophages, reticular cells, follicular dendritic cells, dendritic cells, T cells, plasma cells
cortex
primary cortical cell type
B lymphocyte
phagocitic and humoral immunity is the activity that occurs in the ___ of the lymph node
cortex
- type of lymph nodule that does not have a germinal center
- older nodules where naiive B cells congregate, as well as B memory cells
primary lymphoid nodule
- lymph nodule that does have a germinal center and forms in response to a foreign antigen
- active B cell division
secondary lymphoid nodule
two other names for the paracortex of the lymph node
-thins with HIV
thymus dependent zone
deep cortex
macrophages, reticular, some B, and dendritic cells are all found in the paracortex, but the primary cell type is a
T lymphocyte
-long term storage for T cells (can enlarge w/ Tcell stim)
-phagocytosis
-cell mediated immunity
is all activity that occurs in this area of the lymph node
paracortex
