Glycerylnitrat Flashcards

1
Q

Indikation

glycerylnitrat

A

AKS, herunder STEMI, NSTEMI, UAP og AP

Akut lungeødem

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2
Q

Dosis og alder

glycerylnitrat

A

0,4 mg (1 pust)

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3
Q

Indgiftsmåde

glycerylnitrat

A

Sublingualt

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4
Q

Kontraindikation

glycerylnitrat

A

AKS og AP: Systolisk BT < 90 mmHg

Lungeødem: systolisk BT < 140 mmHg

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5
Q

Bivirkninger

glycerylnitrat

A
Almindelige:
Hovedpine
Ansigtsrødmen
Takykardi
Døsighed

Livstruende:
Svær hypotension

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6
Q

Interaktion

glycerylnitrat

A

Indtagelse af midler mod rejningsproblemer indenfor 24 timer kan udløse svær hypotension

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7
Q

Farmakologi

glycerylnitrat

A

Hurtigtvirkende, kardilaterende organisk nitrat til applicering på mundslimhinden

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8
Q

Farmakokinetik

glycerylnitrat

A

Absorberes næsten fuldstændig fra mundslimhinden

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9
Q

Virkningstid, varighed og halveringstid

glycerylnitrat

A

Virkningstid: ½ - 1 min
Virkningsvarighed: 10-30 min
Halveringstid: 1-3 min

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10
Q

Gentagelse og max dosis

glycerylnitrat

A

Gentagelse: Til kontroindikation nåes

Max dosis: Ingen

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11
Q

Særlige forhold

glycerylnitrat

A
Anvendes med forsigtighed ved: 
Anæmi
Hypertyrodisme
Hypotension med eller uden andre shocktegn. 
Tilstande hvor shock er muligt eller mistænkes. 
Cerebrovaskulær sygdom
Aortastenose
Mitralstenose
Hypertrofisk obstruktiv kardiomyopati
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