E7 Acid-base chemistry in dyspepsia 4

Question 1

complete the equation Total mEq=….

what does each component stand for?

Answer 1

(30 x N{HCl}) - V{NaOH} x N{NaOH})
N-HCl = normality of HCl
N- NaOH = normality of NaOH
V- NaOH = volume NaOH used in titration

Question 2

Why can 1M HCl = 1N HCl

and 1M H2SO4 = 2N H2SO4?

Answer 2

because it produces one equivalent (of protons) per L

because it produces two equivalents (of protons) per L

Question 3

Which are the better acid neutralising and cost effective out of liquids or tablets?

Answer 3

liquids

Question 4

What are the ideal characteristics of antacids?

Answer 4

acts locally (insoluble in water and not absorbed into the circulation) 
maintains pH in the range 3-6
exerts effect swiftly and good duration of action 
does not produce large vol of gas when reacting with HCl 
does not cause laxative effects or constipation

Question 5

What are the +ves of combining a number of antacids in one medication?

Answer 5

optimise the rate of onset of action, duration of action, range of pH reached